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Knit directory: Genomic-Selection-for-Drought-Tolerance-Using-Genome-Wide-SNPs-in-Casava/

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Configurations and packages

To perform the analyses, we will need the following packages:

library(furrr)
library(tidyverse)
library(cvTools)
library(kableExtra)

Data

geno<- readRDS("data/geno.rds")
pheno<-readRDS("data/pheno.rds")
traits <- colnames(pheno)[-1]

RR-BLUP

The Ridge Regression BLUP, or RRBLUP, will predict the marker effect. In the RRBLUP, we will use the matrix of markers directly.

For this purpose, we will use the sommer package [@Covarrubias-Pazaran_2014]. In the code below, y is for the vector with the means, Z is where we will insert the SNPs matrix, K is for a covariance matrix for the random effects, which will be and identity matrix by default; and X is a design matrix for the fixed effects, which will be a vector of ones (1) by default. Note that we are returning to the “1, 0, -1” codification in the SNPs matrix. This is a requirement of the rrBlUP package.

Z <- geno - 1

Cross-validation

To prove that the prediction is accurate, we should perform a cross-validation (CV) scheme. For this purpose, we divide the data into a training set and a validation set.

First we separate the data into k folds. Then, we attribute NA for one fold and try to predict the data from this fold based on the others. When selecting the number of folds, one must prioritize the balance between the number of observations in each fold.

In addition, this process should be repeated for further validation. The step-by-step below will guide the CV in the data we are analysing.

1. Determine the number of folds and repetitions

nfolds = 5
nrept = 5

Since we defined 5 folds, our data will be divided into 5 parts with 83 observations each.

2. Match the order of the data and the rows of the SNP matrix

The order is decreasing or increasing (numeric or alphabetical) regarding the name of the genotypes.

pheno <- pheno[order(pheno$ID_Clone, decreasing = F),]
geno <- geno[order(row.names(geno)),]
all(rownames(geno) == pheno$ID_Clone)
[1] TRUE

3. Add a column indicating a number for each observation

This will be useful to assign each observation for a fold, which will be the next step.

pheno$ID <- factor(1:nrow(pheno))

4. Folds assignment

In this step, we will assign each observation to a fold. Bear in mind that for each repetition, the folds will comprise different observations. The purpose of the repetition is to make sure of the randomness of the assignment step.

In this step, we will use the cvTools package [@cvTools]

For better performance, we included this step in the loop of the next step.

Run model

The next step is the very CV. Here, we will define the linear predictor and the lists that will be useful in the loop. The first list, here called results_cv_RR_BLUP and, contains the results for each fold assignation that we built in the previous step. The second GEBVS_RR_BLUP contains the GEBVs.

Then, we will construct the loop. Each iteration will assign NA for a different fold, and we will use the other folds to predict the missing values. Note that the folds vary for each repetition and trait.

Set up parallel processing. Define and run multiple models to get the GEBVs ATTENTION: This process is time-consuming.

# Planejar o processamento em várias sessões para paralelização
plan(multisession)

# Iniciar uma lista para armazenar os resultados
results_list <-
  future_map(traits, .options = furrr_options(seed = 100), function(j)  {
    # Pré-processamento dos dados
    pheno2 <- pheno %>%
      select(ID_Clone, all_of(j)) %>%
      na.omit() %>%
      ungroup() %>%
      filter(ID_Clone %in% rownames(Z)) %>%
      mutate(ID = factor(1:nrow(.))) %>%
      droplevels()
    
    # Filtrar as linhas de Z com base em pheno2$ID_Clone
    Z1 <- Z[rownames(Z) %in% pheno2$ID_Clone, ]
    
    # Listas das folds
    fold.list <- lapply(1:nrept, function(a) {
      folds <- cvFolds(nlevels(pheno2$ID),
                       type = "random",
                       K = nfolds)
      
      split(folds$subsets, f = folds$which)
    })
    
    # Usar future_map_dfr para criar dobras cruzadas em paralelo
    future_map_dfr(1:length(fold.list), function(z) {
      for (i in 1:nfolds) {
        # Conjunto de treinamento
        train_data <- pheno2
        
        # Conjunto de validação
        train_data[train_data$ID %in% fold.list[[z]][[i]], j] <- NA
        
        # Ajustar o modelo
        fixed <- formula(paste(j, " ~ 1"))
        
        RR_BLUP <-
          sommer::mmer(
            fixed,
            random = ~ sommer::vsr(list(Z1), buildGu = FALSE),
            data = train_data,
            getPEV = FALSE,
            rcov = ~ units
          )
        
        # GEBV (Valores Genômicos Empíricos Melhorados)
        Pred <-
          data.frame(
            Yhat = Z1 %*% RR_BLUP$U$`u:Z1`[[j]],
            ID = train_data$ID,
            ID_Clone = train_data$ID_Clone
          ) %>%
          filter(ID %in% fold.list[[z]][[i]])
        
        result1 <-
          tibble(
            GEBV = Pred$Yhat,
            ID = Pred$ID,
            ID_Clone = Pred$ID_Clone,
            Trait = j,
            rep = z,
            fold = i
          )
        
        # Resultados da previsão
        if (i == 1) {
          result <- result1
        } else {
          result <- rbind(result, result1)
        }
      }
      
      #Ordenando os resultados de acordo com o ID
      result <- result[order(result$ID, decreasing = F),]
      
      # Resultados da validação cruzada
      result_cv <- tibble(
        Trait = j,
        rep = z,
        Log = all(result$ID == pheno2$ID),
        Ac = round(cor(result$GEBV, pheno2[[j]], use = "na.or.complete"), 3),
        MSPE = round(mean((
          result$GEBV - pheno2[[j]]
        ) ^ 2, na.rm = TRUE), 3),
        result = list(result)
      )
    })
  })
iteration    LogLik     wall    cpu(sec)   restrained
    1      -341.922   17:43:33      6           0
    2      -237.384   17:43:33      6           0
    3      -172.743   17:43:33      6           0
    4      -155.375   17:43:33      6           0
    5      -153.314   17:43:34      7           0
    6      -153.075   17:43:34      7           0
    7      -153.053   17:43:34      7           0
    8      -153.051   17:43:34      7           0
    9      -153.051   17:43:34      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -323.713   17:43:41      6           0
    2      -245.639   17:43:42      7           0
    3      -181.744   17:43:42      7           0
    4      -156.469   17:43:42      7           0
    5      -152.69   17:43:42      7           0
    6      -152.373   17:43:42      7           0
    7      -152.362   17:43:42      7           0
    8      -152.362   17:43:42      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -358.341   17:43:50      7           0
    2      -268.2   17:43:50      7           0
    3      -189.947   17:43:50      7           0
    4      -156.272   17:43:50      7           0
    5      -154.728   17:43:50      7           0
    6      -154.727   17:43:51      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -335.776   17:43:58      7           0
    2      -248.293   17:43:58      7           0
    3      -183.323   17:43:58      7           0
    4      -159.308   17:43:58      7           0
    5      -156.081   17:43:58      7           0
    6      -155.686   17:43:59      8           0
    7      -155.645   17:43:59      8           0
    8      -155.641   17:43:59      8           0
    9      -155.641   17:43:59      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -327.26   17:44:6      6           0
    2      -241.485   17:44:6      6           0
    3      -180.923   17:44:6      6           0
    4      -158.721   17:44:7      7           0
    5      -155.112   17:44:7      7           0
    6      -154.558   17:44:7      7           0
    7      -154.493   17:44:7      7           0
    8      -154.487   17:44:7      7           0
    9      -154.487   17:44:7      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -333.124   17:44:15      7           0
    2      -247.311   17:44:15      7           0
    3      -183.523   17:44:15      7           0
    4      -157.206   17:44:15      7           0
    5      -153.35   17:44:15      7           0
    6      -153.009   17:44:15      7           0
    7      -152.997   17:44:15      7           0
    8      -152.996   17:44:16      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -343.822   17:44:23      7           0
    2      -232.846   17:44:23      7           0
    3      -170.317   17:44:23      7           0
    4      -152.498   17:44:23      7           0
    5      -151.328   17:44:23      7           0
    6      -151.283   17:44:24      8           0
    7      -151.282   17:44:24      8           0
    8      -151.282   17:44:24      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -332.995   17:44:31      7           0
    2      -257.444   17:44:31      7           0
    3      -187.035   17:44:31      7           0
    4      -158.63   17:44:32      8           0
    5      -155.273   17:44:32      8           0
    6      -154.984   17:44:32      8           0
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iteration    LogLik     wall    cpu(sec)   restrained
    1      -320.631   17:44:40      7           0
    2      -247.196   17:44:40      7           0
    3      -186.075   17:44:40      7           0
    4      -159.716   17:44:40      7           0
    5      -154.932   17:44:40      7           0
    6      -154.226   17:44:40      7           0
    7      -154.153   17:44:41      8           0
    8      -154.148   17:44:41      8           0
    9      -154.147   17:44:41      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -356.484   17:44:48      7           0
    2      -255.642   17:44:48      7           0
    3      -182.426   17:44:48      7           0
    4      -157.28   17:44:48      7           0
    5      -155.396   17:44:49      8           0
    6      -155.366   17:44:49      8           0
    7      -155.366   17:44:49      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -349.263   17:44:56      6           0
    2      -246.582   17:44:56      6           0
    3      -174.132   17:44:56      6           0
    4      -152.706   17:44:56      6           0
    5      -151.681   17:44:57      7           0
    6      -151.669   17:44:57      7           0
    7      -151.669   17:44:57      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -346.947   17:45:4      6           0
    2      -248.208   17:45:4      6           0
    3      -180.314   17:45:5      7           0
    4      -155.646   17:45:5      7           0
    5      -153.341   17:45:5      7           0
    6      -153.246   17:45:5      7           0
    7      -153.244   17:45:5      7           0
    8      -153.244   17:45:5      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -326.221   17:45:13      7           0
    2      -245.147   17:45:13      7           0
    3      -184.397   17:45:13      7           0
    4      -159.3   17:45:13      7           0
    5      -155.234   17:45:13      7           0
    6      -154.629   17:45:13      7           0
    7      -154.556   17:45:13      7           0
    8      -154.549   17:45:14      8           0
    9      -154.549   17:45:14      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -334.013   17:45:21      7           0
    2      -250.401   17:45:21      7           0
    3      -186.285   17:45:21      7           0
    4      -160.73   17:45:21      7           0
    5      -156.524   17:45:22      8           0
    6      -156.038   17:45:22      8           0
    7      -156   17:45:22      8           0
    8      -155.998   17:45:22      8           0
    9      -155.997   17:45:22      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -345.958   17:45:29      6           0
    2      -251.478   17:45:30      7           0
    3      -181.891   17:45:30      7           0
    4      -159.341   17:45:30      7           0
    5      -156.352   17:45:30      7           0
    6      -156.034   17:45:30      7           0
    7      -156.014   17:45:30      7           0
    8      -156.013   17:45:30      7           0
    9      -156.012   17:45:31      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -331.904   17:45:38      7           0
    2      -255.727   17:45:38      7           0
    3      -184.938   17:45:38      7           0
    4      -156.146   17:45:38      7           0
    5      -153.194   17:45:38      7           0
    6      -152.967   17:45:39      8           0
    7      -152.955   17:45:39      8           0
    8      -152.954   17:45:39      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -343.348   17:45:46      7           0
    2      -256.4   17:45:46      7           0
    3      -187.628   17:45:46      7           0
    4      -160.159   17:45:46      7           0
    5      -156.181   17:45:46      7           0
    6      -155.919   17:45:47      8           0
    7      -155.916   17:45:47      8           0
    8      -155.916   17:45:47      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -333.612   17:45:54      7           0
    2      -246.349   17:45:54      7           0
    3      -180.435   17:45:54      7           0
    4      -158.04   17:45:54      7           0
    5      -155.307   17:45:54      7           0
    6      -154.935   17:45:55      8           0
    7      -154.893   17:45:55      8           0
    8      -154.888   17:45:55      8           0
    9      -154.888   17:45:55      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -355.013   17:46:2      6           0
    2      -251.837   17:46:2      6           0
    3      -183.392   17:46:2      6           0
    4      -157.647   17:46:3      7           0
    5      -155.82   17:46:3      7           0
    6      -155.782   17:46:3      7           0
    7      -155.782   17:46:3      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -320.544   17:46:10      6           0
    2      -229.082   17:46:10      6           0
    3      -171.678   17:46:10      6           0
    4      -153.699   17:46:10      6           0
    5      -150.913   17:46:11      7           0
    6      -150.526   17:46:11      7           0
    7      -150.481   17:46:11      7           0
    8      -150.477   17:46:11      7           0
    9      -150.476   17:46:11      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -336.135   17:46:18      6           0
    2      -244.677   17:46:18      6           0
    3      -187.557   17:46:19      7           0
    4      -164.093   17:46:19      7           0
    5      -158.633   17:46:19      7           0
    6      -157.603   17:46:19      7           0
    7      -157.522   17:46:19      7           0
    8      -157.52   17:46:19      7           0
    9      -157.52   17:46:19      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -344.989   17:46:26      6           0
    2      -244.008   17:46:27      7           0
    3      -172.403   17:46:27      7           0
    4      -153.249   17:46:27      7           0
    5      -151.728   17:46:27      7           0
    6      -151.633   17:46:27      7           0
    7      -151.629   17:46:27      7           0
    8      -151.629   17:46:27      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -310.773   17:46:34      6           0
    2      -238.371   17:46:35      7           0
    3      -178.395   17:46:35      7           0
    4      -153.579   17:46:35      7           0
    5      -149.996   17:46:35      7           0
    6      -149.712   17:46:35      7           0
    7      -149.697   17:46:35      7           0
    8      -149.696   17:46:35      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -328.868   17:46:43      7           0
    2      -249.14   17:46:43      7           0
    3      -183.545   17:46:43      7           0
    4      -158.163   17:46:43      7           0
    5      -154.568   17:46:43      7           0
    6      -154.205   17:46:43      7           0
    7      -154.182   17:46:43      7           0
    8      -154.181   17:46:44      8           0
    9      -154.181   17:46:44      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -364.618   17:46:51      7           0
    2      -261.086   17:46:51      7           0
    3      -180.337   17:46:51      7           0
    4      -154.382   17:46:51      7           0
    5      -153.623   17:46:51      7           0
    6      -153.619   17:46:51      7           0
    7      -153.619   17:46:51      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -314.123   17:43:34      7           0
    2      -220.89   17:43:34      7           0
    3      -162.469   17:43:34      7           0
    4      -148.655   17:43:34      7           0
    5      -147.388   17:43:34      7           0
    6      -147.216   17:43:34      7           0
    7      -147.191   17:43:35      8           0
    8      -147.187   17:43:35      8           0
    9      -147.187   17:43:35      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -292.04   17:43:42      6           0
    2      -216.25   17:43:42      6           0
    3      -164.263   17:43:42      6           0
    4      -151.202   17:43:43      7           0
    5      -148.896   17:43:43      7           0
    6      -148.231   17:43:43      7           0
    7      -148.02   17:43:43      7           0
    8      -147.954   17:43:43      7           0
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    10      -147.927   17:43:43      7           0
    11      -147.926   17:43:44      8           0
    12      -147.925   17:43:44      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -287.378   17:43:51      6           0
    2      -210.323   17:43:51      6           0
    3      -159.514   17:43:52      7           0
    4      -146.872   17:43:52      7           0
    5      -144.806   17:43:52      7           0
    6      -144.28   17:43:52      7           0
    7      -144.135   17:43:52      7           0
    8      -144.094   17:43:52      7           0
    9      -144.083   17:43:52      7           0
    10      -144.081   17:43:53      8           0
    11      -144.08   17:43:53      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -302.39   17:44:0      7           0
    2      -215.507   17:44:0      7           0
    3      -156.969   17:44:0      7           0
    4      -142.32   17:44:0      7           0
    5      -140.877   17:44:1      8           0
    6      -140.689   17:44:1      8           0
    7      -140.665   17:44:1      8           0
    8      -140.662   17:44:1      8           0
    9      -140.662   17:44:1      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -293.74   17:44:8      6           0
    2      -210.388   17:44:9      7           0
    3      -164.203   17:44:9      7           0
    4      -151.86   17:44:9      7           0
    5      -149.568   17:44:9      7           0
    6      -148.942   17:44:9      7           0
    7      -148.753   17:44:9      7           0
    8      -148.695   17:44:10      8           0
    9      -148.677   17:44:10      8           0
    10      -148.672   17:44:10      8           0
    11      -148.67   17:44:10      8           0
    12      -148.67   17:44:10      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -257.547   17:44:18      7           0
    2      -193.899   17:44:18      7           0
    3      -151.1   17:44:18      7           0
    4      -140.603   17:44:18      7           0
    5      -139.308   17:44:18      7           0
    6      -139.027   17:44:18      7           0
    7      -138.951   17:44:19      8           0
    8      -138.929   17:44:19      8           0
    9      -138.922   17:44:19      8           0
    10      -138.92   17:44:19      8           0
    11      -138.92   17:44:19      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -297.11   17:44:26      6           0
    2      -215.711   17:44:27      7           0
    3      -163.239   17:44:27      7           0
    4      -149.535   17:44:27      7           0
    5      -147.267   17:44:27      7           0
    6      -146.731   17:44:27      7           0
    7      -146.6   17:44:27      7           0
    8      -146.568   17:44:27      7           0
    9      -146.561   17:44:28      8           0
    10      -146.559   17:44:28      8           0
    11      -146.559   17:44:28      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -319.397   17:44:35      7           0
    2      -225.09   17:44:35      7           0
    3      -160.479   17:44:35      7           0
    4      -144.99   17:44:35      7           0
    5      -143.864   17:44:36      8           0
    6      -143.781   17:44:36      8           0
    7      -143.776   17:44:36      8           0
    8      -143.775   17:44:36      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -320.582   17:44:43      6           0
    2      -228.88   17:44:43      6           0
    3      -170.827   17:44:44      7           0
    4      -154.882   17:44:44      7           0
    5      -152.101   17:44:44      7           0
    6      -151.487   17:44:44      7           0
    7      -151.372   17:44:44      7           0
    8      -151.354   17:44:44      7           0
    9      -151.352   17:44:44      7           0
    10      -151.352   17:44:45      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -277.035   17:44:52      7           0
    2      -201.736   17:44:52      7           0
    3      -156.318   17:44:52      7           0
    4      -145.179   17:44:52      7           0
    5      -143.568   17:44:52      7           0
    6      -143.195   17:44:52      7           0
    7      -143.095   17:44:53      8           0
    8      -143.066   17:44:53      8           0
    9      -143.058   17:44:53      8           0
    10      -143.056   17:44:53      8           0
    11      -143.055   17:44:53      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -288.254   17:45:1      7           0
    2      -204.897   17:45:1      7           0
    3      -158.099   17:45:1      7           0
    4      -147.856   17:45:1      7           0
    5      -146.361   17:45:1      7           0
    6      -145.993   17:45:1      7           0
    7      -145.886   17:45:2      8           0
    8      -145.853   17:45:2      8           0
    9      -145.843   17:45:2      8           0
    10      -145.839   17:45:2      8           0
    11      -145.838   17:45:2      8           0
    12      -145.838   17:45:2      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -310.358   17:45:10      7           0
    2      -217.47   17:45:10      7           0
    3      -161.052   17:45:10      7           0
    4      -146.265   17:45:10      7           0
    5      -144.177   17:45:10      7           0
    6      -143.811   17:45:10      7           0
    7      -143.753   17:45:10      7           0
    8      -143.745   17:45:11      8           0
    9      -143.744   17:45:11      8           0
    10      -143.744   17:45:11      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -292.999   17:45:18      6           0
    2      -208.645   17:45:18      6           0
    3      -157.954   17:45:18      6           0
    4      -144.838   17:45:19      7           0
    5      -143.249   17:45:19      7           0
    6      -142.975   17:45:19      7           0
    7      -142.925   17:45:19      7           0
    8      -142.916   17:45:19      7           0
    9      -142.915   17:45:19      7           0
    10      -142.914   17:45:19      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -302.305   17:45:27      7           0
    2      -204.556   17:45:27      7           0
    3      -158.41   17:45:27      7           0
    4      -147.958   17:45:27      7           0
    5      -146.324   17:45:27      7           0
    6      -145.988   17:45:27      7           0
    7      -145.919   17:45:27      7           0
    8      -145.905   17:45:28      8           0
    9      -145.903   17:45:28      8           0
    10      -145.902   17:45:28      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -292.3   17:45:35      6           0
    2      -216.886   17:45:35      6           0
    3      -164.417   17:45:36      7           0
    4      -149.693   17:45:36      7           0
    5      -147.106   17:45:36      7           0
    6      -146.469   17:45:36      7           0
    7      -146.313   17:45:36      7           0
    8      -146.277   17:45:36      7           0
    9      -146.269   17:45:36      7           0
    10      -146.267   17:45:37      8           0
    11      -146.267   17:45:37      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -296.849   17:45:44      7           0
    2      -215.608   17:45:44      7           0
    3      -165.095   17:45:44      7           0
    4      -151.544   17:45:44      7           0
    5      -149.22   17:45:45      8           0
    6      -148.638   17:45:45      8           0
    7      -148.478   17:45:45      8           0
    8      -148.434   17:45:45      8           0
    9      -148.421   17:45:45      8           0
    10      -148.418   17:45:45      8           0
    11      -148.417   17:45:45      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -295.771   17:45:52      6           0
    2      -209.604   17:45:53      7           0
    3      -163.409   17:45:53      7           0
    4      -151.357   17:45:53      7           0
    5      -148.974   17:45:53      7           0
    6      -148.276   17:45:53      7           0
    7      -148.06   17:45:53      7           0
    8      -147.996   17:45:53      7           0
    9      -147.978   17:45:54      8           0
    10      -147.973   17:45:54      8           0
    11      -147.971   17:45:54      8           0
    12      -147.971   17:45:54      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -287.199   17:46:1      6           0
    2      -203.736   17:46:1      6           0
    3      -156.692   17:46:1      6           0
    4      -144.889   17:46:1      6           0
    5      -143.178   17:46:2      7           0
    6      -142.811   17:46:2      7           0
    7      -142.726   17:46:2      7           0
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    9      -142.701   17:46:2      7           0
    10      -142.7   17:46:2      7           0
    11      -142.7   17:46:2      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -304.609   17:46:10      7           0
    2      -213.166   17:46:10      7           0
    3      -155.708   17:46:10      7           0
    4      -143.559   17:46:10      7           0
    5      -142.469   17:46:10      7           0
    6      -142.319   17:46:10      7           0
    7      -142.298   17:46:10      7           0
    8      -142.295   17:46:11      8           0
    9      -142.294   17:46:11      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -308.362   17:46:18      7           0
    2      -213.874   17:46:18      7           0
    3      -160.356   17:46:18      7           0
    4      -147.723   17:46:18      7           0
    5      -145.89   17:46:18      7           0
    6      -145.508   17:46:18      7           0
    7      -145.429   17:46:19      8           0
    8      -145.414   17:46:19      8           0
    9      -145.411   17:46:19      8           0
    10      -145.411   17:46:19      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -304.04   17:46:26      6           0
    2      -210.242   17:46:26      6           0
    3      -160.332   17:46:26      6           0
    4      -148.097   17:46:27      7           0
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    9      -145.72   17:46:27      7           0
    10      -145.719   17:46:27      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -281.258   17:46:35      7           0
    2      -202.136   17:46:35      7           0
    3      -159.028   17:46:35      7           0
    4      -148.879   17:46:35      7           0
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    10      -146.41   17:46:36      8           0
    11      -146.408   17:46:36      8           0
    12      -146.407   17:46:36      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -286.155   17:46:44      7           0
    2      -206.473   17:46:44      7           0
    3      -156.956   17:46:44      7           0
    4      -145.033   17:46:44      7           0
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    8      -143.128   17:46:45      8           0
    9      -143.125   17:46:45      8           0
    10      -143.124   17:46:45      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -301.16   17:46:52      6           0
    2      -221.416   17:46:52      6           0
    3      -166.219   17:46:53      7           0
    4      -148.49   17:46:53      7           0
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    6      -144.801   17:46:53      7           0
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    9      -144.688   17:46:53      7           0
    10      -144.688   17:46:54      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -298.642   17:47:0      6           0
    2      -211.832   17:47:1      7           0
    3      -160.547   17:47:1      7           0
    4      -148.575   17:47:1      7           0
    5      -146.797   17:47:1      7           0
    6      -146.383   17:47:1      7           0
    7      -146.277   17:47:1      7           0
    8      -146.249   17:47:1      7           0
    9      -146.242   17:47:2      8           0
    10      -146.24   17:47:2      8           0
    11      -146.24   17:47:2      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -306.346   17:43:34      6           0
    2      -221.703   17:43:34      6           0
    3      -168.488   17:43:34      6           0
    4      -154.904   17:43:35      7           0
    5      -152.868   17:43:35      7           0
    6      -152.394   17:43:35      7           0
    7      -152.267   17:43:35      7           0
    8      -152.231   17:43:35      7           0
    9      -152.22   17:43:35      7           0
    10      -152.217   17:43:36      8           0
    11      -152.216   17:43:36      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -314.252   17:43:43      6           0
    2      -229.315   17:43:43      6           0
    3      -172.609   17:43:44      7           0
    4      -156.061   17:43:44      7           0
    5      -153.752   17:43:44      7           0
    6      -153.273   17:43:44      7           0
    7      -153.165   17:43:44      7           0
    8      -153.139   17:43:44      7           0
    9      -153.134   17:43:45      8           0
    10      -153.132   17:43:45      8           0
    11      -153.132   17:43:45      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -305.056   17:43:52      6           0
    2      -220.289   17:43:53      7           0
    3      -157.119   17:43:53      7           0
    4      -143.987   17:43:53      7           0
    5      -143.31   17:43:53      7           0
    6      -143.249   17:43:53      7           0
    7      -143.243   17:43:53      7           0
    8      -143.242   17:43:53      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -301.804   17:44:1      7           0
    2      -217.873   17:44:1      7           0
    3      -162.113   17:44:1      7           0
    4      -150.363   17:44:1      7           0
    5      -149.226   17:44:2      8           0
    6      -149.039   17:44:2      8           0
    7      -149.002   17:44:2      8           0
    8      -148.995   17:44:2      8           0
    9      -148.993   17:44:2      8           0
    10      -148.993   17:44:2      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -325.854   17:44:10      7           0
    2      -221.757   17:44:10      7           0
    3      -167.257   17:44:10      7           0
    4      -153.178   17:44:10      7           0
    5      -150.862   17:44:10      7           0
    6      -150.333   17:44:10      7           0
    7      -150.222   17:44:11      8           0
    8      -150.202   17:44:11      8           0
    9      -150.199   17:44:11      8           0
    10      -150.199   17:44:11      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -304.052   17:44:19      7           0
    2      -213.183   17:44:19      7           0
    3      -162.256   17:44:19      7           0
    4      -150.514   17:44:19      7           0
    5      -149.163   17:44:19      7           0
    6      -148.924   17:44:19      7           0
    7      -148.874   17:44:20      8           0
    8      -148.863   17:44:20      8           0
    9      -148.861   17:44:20      8           0
    10      -148.86   17:44:20      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -325.824   17:44:27      6           0
    2      -234.928   17:44:28      7           0
    3      -163.762   17:44:28      7           0
    4      -145.051   17:44:28      7           0
    5      -143.648   17:44:28      7           0
    6      -143.555   17:44:28      7           0
    7      -143.551   17:44:28      7           0
    8      -143.551   17:44:29      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -310.511   17:44:36      7           0
    2      -218.449   17:44:36      7           0
    3      -164.142   17:44:36      7           0
    4      -150.966   17:44:36      7           0
    5      -149.298   17:44:36      7           0
    6      -148.959   17:44:37      8           0
    7      -148.882   17:44:37      8           0
    8      -148.864   17:44:37      8           0
    9      -148.86   17:44:37      8           0
    10      -148.859   17:44:37      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -308.58   17:44:45      7           0
    2      -226.976   17:44:45      7           0
    3      -167.933   17:44:45      7           0
    4      -153.84   17:44:45      7           0
    5      -152.612   17:44:45      7           0
    6      -152.429   17:44:46      8           0
    7      -152.396   17:44:46      8           0
    8      -152.389   17:44:46      8           0
    9      -152.388   17:44:46      8           0
    10      -152.388   17:44:46      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -305.478   17:44:53      6           0
    2      -209.417   17:44:54      7           0
    3      -161.452   17:44:54      7           0
    4      -151.588   17:44:54      7           0
    5      -150.446   17:44:54      7           0
    6      -150.222   17:44:54      7           0
    7      -150.169   17:44:54      7           0
    8      -150.155   17:44:55      8           0
    9      -150.152   17:44:55      8           0
    10      -150.151   17:44:55      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -300.628   17:45:2      6           0
    2      -218.125   17:45:2      6           0
    3      -165.897   17:45:3      7           0
    4      -153.495   17:45:3      7           0
    5      -151.849   17:45:3      7           0
    6      -151.504   17:45:3      7           0
    7      -151.42   17:45:3      7           0
    8      -151.398   17:45:3      7           0
    9      -151.392   17:45:4      8           0
    10      -151.39   17:45:4      8           0
    11      -151.39   17:45:4      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -303.894   17:45:11      6           0
    2      -213.232   17:45:12      7           0
    3      -159.884   17:45:12      7           0
    4      -146.586   17:45:12      7           0
    5      -145.091   17:45:12      7           0
    6      -144.868   17:45:12      7           0
    7      -144.833   17:45:12      7           0
    8      -144.827   17:45:13      8           0
    9      -144.826   17:45:13      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -308.076   17:45:20      7           0
    2      -223.294   17:45:20      7           0
    3      -167.398   17:45:20      7           0
    4      -153.828   17:45:21      8           0
    5      -152.257   17:45:21      8           0
    6      -151.942   17:45:21      8           0
    7      -151.866   17:45:21      8           0
    8      -151.846   17:45:21      8           0
    9      -151.84   17:45:21      8           0
    10      -151.839   17:45:22      9           0
    11      -151.838   17:45:22      9           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -313.735   17:45:29      7           0
    2      -231.912   17:45:29      7           0
    3      -168.21   17:45:29      7           0
    4      -151.54   17:45:29      7           0
    5      -150.16   17:45:30      8           0
    6      -149.961   17:45:30      8           0
    7      -149.927   17:45:30      8           0
    8      -149.921   17:45:30      8           0
    9      -149.92   17:45:30      8           0
    10      -149.92   17:45:30      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -323.234   17:45:38      7           0
    2      -223.349   17:45:38      7           0
    3      -167.254   17:45:38      7           0
    4      -154.234   17:45:38      7           0
    5      -152.357   17:45:38      7           0
    6      -151.94   17:45:39      8           0
    7      -151.843   17:45:39      8           0
    8      -151.821   17:45:39      8           0
    9      -151.816   17:45:39      8           0
    10      -151.815   17:45:39      8           0
    11      -151.814   17:45:39      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -303.104   17:45:47      7           0
    2      -220.13   17:45:47      7           0
    3      -164.089   17:45:47      7           0
    4      -149.988   17:45:47      7           0
    5      -148.296   17:45:47      7           0
    6      -147.975   17:45:47      7           0
    7      -147.905   17:45:48      8           0
    8      -147.889   17:45:48      8           0
    9      -147.885   17:45:48      8           0
    10      -147.884   17:45:48      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -321.827   17:45:55      6           0
    2      -238.579   17:45:55      6           0
    3      -168.975   17:45:55      6           0
    4      -150.813   17:45:56      7           0
    5      -149.544   17:45:56      7           0
    6      -149.407   17:45:56      7           0
    7      -149.391   17:45:56      7           0
    8      -149.389   17:45:56      7           0
    9      -149.389   17:45:56      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -304.017   17:46:3      6           0
    2      -214.073   17:46:4      7           0
    3      -158.488   17:46:4      7           0
    4      -146.193   17:46:4      7           0
    5      -145.189   17:46:4      7           0
    6      -145.063   17:46:4      7           0
    7      -145.044   17:46:4      7           0
    8      -145.042   17:46:4      7           0
    9      -145.041   17:46:5      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -316.415   17:46:12      7           0
    2      -228.972   17:46:12      7           0
    3      -174.177   17:46:12      7           0
    4      -158.036   17:46:12      7           0
    5      -155.101   17:46:13      8           0
    6      -154.368   17:46:13      8           0
    7      -154.186   17:46:13      8           0
    8      -154.145   17:46:13      8           0
    9      -154.137   17:46:13      8           0
    10      -154.135   17:46:13      8           0
    11      -154.135   17:46:14      9           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -312.749   17:46:21      7           0
    2      -215.877   17:46:21      7           0
    3      -163.582   17:46:21      7           0
    4      -152.647   17:46:21      7           0
    5      -151.443   17:46:21      7           0
    6      -151.219   17:46:21      7           0
    7      -151.169   17:46:22      8           0
    8      -151.157   17:46:22      8           0
    9      -151.155   17:46:22      8           0
    10      -151.154   17:46:22      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -325.557   17:46:29      6           0
    2      -237.535   17:46:30      7           0
    3      -177.382   17:46:30      7           0
    4      -159.71   17:46:30      7           0
    5      -157.17   17:46:30      7           0
    6      -156.674   17:46:30      7           0
    7      -156.572   17:46:30      7           0
    8      -156.552   17:46:30      7           0
    9      -156.548   17:46:31      8           0
    10      -156.547   17:46:31      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -307.552   17:46:38      7           0
    2      -216.386   17:46:38      7           0
    3      -163.992   17:46:38      7           0
    4      -152.497   17:46:38      7           0
    5      -150.993   17:46:39      8           0
    6      -150.655   17:46:39      8           0
    7      -150.565   17:46:39      8           0
    8      -150.539   17:46:39      8           0
    9      -150.531   17:46:39      8           0
    10      -150.529   17:46:39      8           0
    11      -150.528   17:46:39      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -296.652   17:46:47      7           0
    2      -213.93   17:46:47      7           0
    3      -160.717   17:46:47      7           0
    4      -148.278   17:46:47      7           0
    5      -146.851   17:46:47      7           0
    6      -146.575   17:46:47      7           0
    7      -146.513   17:46:48      8           0
    8      -146.498   17:46:48      8           0
    9      -146.494   17:46:48      8           0
    10      -146.493   17:46:48      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -305.107   17:46:55      6           0
    2      -216.874   17:46:55      6           0
    3      -160.684   17:46:56      7           0
    4      -148.166   17:46:56      7           0
    5      -146.915   17:46:56      7           0
    6      -146.703   17:46:56      7           0
    7      -146.662   17:46:56      7           0
    8      -146.653   17:46:56      7           0
    9      -146.651   17:46:57      8           0
    10      -146.651   17:46:57      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -307.77   17:47:4      7           0
    2      -228.116   17:47:4      7           0
    3      -169.946   17:47:4      7           0
    4      -152.459   17:47:4      7           0
    5      -150.419   17:47:4      7           0
    6      -150.108   17:47:4      7           0
    7      -150.056   17:47:5      8           0
    8      -150.047   17:47:5      8           0
    9      -150.045   17:47:5      8           0
    10      -150.045   17:47:5      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -264.714   17:43:32      4           0
    2      -180.76   17:43:32      4           0
    3      -129.631   17:43:32      4           0
    4      -118.312   17:43:32      4           0
    5      -117.64   17:43:32      4           0
    6      -117.604   17:43:32      4           0
    7      -117.602   17:43:32      4           0
    8      -117.602   17:43:32      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -240.528   17:43:37      4           0
    2      -163.161   17:43:37      4           0
    3      -123.05   17:43:37      4           0
    4      -114.444   17:43:37      4           0
    5      -113.58   17:43:37      4           0
    6      -113.476   17:43:37      4           0
    7      -113.464   17:43:37      4           0
    8      -113.462   17:43:37      4           0
    9      -113.462   17:43:38      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -243.341   17:43:42      4           0
    2      -168.53   17:43:42      4           0
    3      -126.326   17:43:42      4           0
    4      -118.209   17:43:42      4           0
    5      -117.399   17:43:42      4           0
    6      -117.271   17:43:42      4           0
    7      -117.248   17:43:42      4           0
    8      -117.243   17:43:42      4           0
    9      -117.243   17:43:43      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -257.961   17:43:47      4           0
    2      -179.926   17:43:47      4           0
    3      -134.437   17:43:47      4           0
    4      -122.113   17:43:47      4           0
    5      -120.365   17:43:47      4           0
    6      -120.138   17:43:47      4           0
    7      -120.114   17:43:47      4           0
    8      -120.111   17:43:48      5           0
    9      -120.111   17:43:48      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -229.532   17:43:52      4           0
    2      -159.82   17:43:52      4           0
    3      -122.635   17:43:52      4           0
    4      -113.287   17:43:52      4           0
    5      -112.26   17:43:52      4           0
    6      -112.142   17:43:52      4           0
    7      -112.128   17:43:53      5           0
    8      -112.127   17:43:53      5           0
    9      -112.126   17:43:53      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -249.589   17:43:57      4           0
    2      -173.339   17:43:57      4           0
    3      -129.671   17:43:57      4           0
    4      -119.629   17:43:57      4           0
    5      -118.645   17:43:58      5           0
    6      -118.529   17:43:58      5           0
    7      -118.513   17:43:58      5           0
    8      -118.511   17:43:58      5           0
    9      -118.511   17:43:58      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -230.929   17:44:2      4           0
    2      -167.883   17:44:2      4           0
    3      -127.652   17:44:2      4           0
    4      -116.956   17:44:3      5           0
    5      -115.452   17:44:3      5           0
    6      -115.208   17:44:3      5           0
    7      -115.169   17:44:3      5           0
    8      -115.163   17:44:3      5           0
    9      -115.162   17:44:3      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -239.725   17:44:7      4           0
    2      -178.637   17:44:7      4           0
    3      -132.274   17:44:7      4           0
    4      -117.923   17:44:7      4           0
    5      -115.917   17:44:7      4           0
    6      -115.627   17:44:8      5           0
    7      -115.591   17:44:8      5           0
    8      -115.587   17:44:8      5           0
    9      -115.586   17:44:8      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -263.683   17:44:12      4           0
    2      -184.069   17:44:12      4           0
    3      -135.426   17:44:12      4           0
    4      -122.498   17:44:13      5           0
    5      -120.991   17:44:13      5           0
    6      -120.757   17:44:13      5           0
    7      -120.72   17:44:13      5           0
    8      -120.714   17:44:13      5           0
    9      -120.713   17:44:13      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -239.736   17:44:17      4           0
    2      -156.87   17:44:17      4           0
    3      -119.118   17:44:17      4           0
    4      -112.15   17:44:17      4           0
    5      -111.556   17:44:17      4           0
    6      -111.494   17:44:18      5           0
    7      -111.487   17:44:18      5           0
    8      -111.486   17:44:18      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -243.038   17:44:22      4           0
    2      -167.268   17:44:22      4           0
    3      -125.533   17:44:22      4           0
    4      -115.163   17:44:22      4           0
    5      -113.979   17:44:22      4           0
    6      -113.838   17:44:22      4           0
    7      -113.822   17:44:22      4           0
    8      -113.821   17:44:22      4           0
    9      -113.821   17:44:23      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -253.047   17:44:27      4           0
    2      -180.237   17:44:27      4           0
    3      -134.353   17:44:27      4           0
    4      -121.994   17:44:27      4           0
    5      -120.206   17:44:27      4           0
    6      -119.887   17:44:27      4           0
    7      -119.829   17:44:27      4           0
    8      -119.819   17:44:27      4           0
    9      -119.817   17:44:27      4           0
    10      -119.817   17:44:28      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -231.986   17:44:32      4           0
    2      -149.883   17:44:32      4           0
    3      -121.876   17:44:32      4           0
    4      -115.633   17:44:32      4           0
    5      -114.727   17:44:32      4           0
    6      -114.56   17:44:32      4           0
    7      -114.526   17:44:32      4           0
    8      -114.52   17:44:32      4           0
    9      -114.518   17:44:32      4           0
    10      -114.518   17:44:33      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -239.533   17:44:37      4           0
    2      -171.918   17:44:37      4           0
    3      -129.334   17:44:37      4           0
    4      -119.303   17:44:37      4           0
    5      -117.98   17:44:37      4           0
    6      -117.738   17:44:37      4           0
    7      -117.691   17:44:37      4           0
    8      -117.682   17:44:38      5           0
    9      -117.68   17:44:38      5           0
    10      -117.68   17:44:38      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -270.768   17:44:42      4           0
    2      -191.86   17:44:42      4           0
    3      -131.543   17:44:42      4           0
    4      -118.494   17:44:42      4           0
    5      -118.196   17:44:42      4           0
    6      -118.187   17:44:42      4           0
    7      -118.187   17:44:42      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -255.868   17:44:47      4           0
    2      -181.661   17:44:47      4           0
    3      -133.93   17:44:47      4           0
    4      -121.926   17:44:47      4           0
    5      -120.224   17:44:47      4           0
    6      -119.92   17:44:47      4           0
    7      -119.867   17:44:47      4           0
    8      -119.858   17:44:47      4           0
    9      -119.856   17:44:47      4           0
    10      -119.856   17:44:47      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -233.91   17:44:52      4           0
    2      -167.353   17:44:52      4           0
    3      -125.933   17:44:52      4           0
    4      -116.424   17:44:52      4           0
    5      -115.304   17:44:52      4           0
    6      -115.113   17:44:52      4           0
    7      -115.077   17:44:52      4           0
    8      -115.071   17:44:52      4           0
    9      -115.07   17:44:52      4           0
    10      -115.069   17:44:53      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -255.878   17:44:57      4           0
    2      -170.14   17:44:57      4           0
    3      -123.654   17:44:57      4           0
    4      -114.361   17:44:57      4           0
    5      -113.839   17:44:57      4           0
    6      -113.81   17:44:57      4           0
    7      -113.809   17:44:57      4           0
    8      -113.809   17:44:57      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -240.898   17:45:2      4           0
    2      -165.324   17:45:2      4           0
    3      -126.834   17:45:2      4           0
    4      -117.607   17:45:2      4           0
    5      -116.486   17:45:2      4           0
    6      -116.327   17:45:2      4           0
    7      -116.304   17:45:2      4           0
    8      -116.3   17:45:2      4           0
    9      -116.3   17:45:2      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -234.632   17:45:7      4           0
    2      -176.108   17:45:7      4           0
    3      -133.102   17:45:7      4           0
    4      -119.746   17:45:7      4           0
    5      -117.931   17:45:7      4           0
    6      -117.666   17:45:7      4           0
    7      -117.626   17:45:7      4           0
    8      -117.62   17:45:7      4           0
    9      -117.619   17:45:7      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -259.256   17:45:11      3           0
    2      -174.967   17:45:11      3           0
    3      -129.551   17:45:12      4           0
    4      -118.279   17:45:12      4           0
    5      -117.192   17:45:12      4           0
    6      -117.106   17:45:12      4           0
    7      -117.1   17:45:12      4           0
    8      -117.1   17:45:12      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -256.789   17:45:16      4           0
    2      -184.436   17:45:16      4           0
    3      -132.11   17:45:16      4           0
    4      -118.991   17:45:16      4           0
    5      -118.163   17:45:16      4           0
    6      -118.096   17:45:17      5           0
    7      -118.09   17:45:17      5           0
    8      -118.09   17:45:17      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -256.572   17:45:21      4           0
    2      -163.65   17:45:21      4           0
    3      -122   17:45:21      4           0
    4      -115.194   17:45:21      4           0
    5      -114.815   17:45:21      4           0
    6      -114.787   17:45:22      5           0
    7      -114.785   17:45:22      5           0
    8      -114.785   17:45:22      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -229.237   17:45:26      4           0
    2      -157.537   17:45:26      4           0
    3      -124.963   17:45:26      4           0
    4      -117.503   17:45:26      4           0
    5      -116.308   17:45:26      4           0
    6      -116.057   17:45:26      4           0
    7      -116   17:45:27      5           0
    8      -115.987   17:45:27      5           0
    9      -115.984   17:45:27      5           0
    10      -115.983   17:45:27      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -225.194   17:45:31      4           0
    2      -165.934   17:45:31      4           0
    3      -128.954   17:45:31      4           0
    4      -118.274   17:45:31      4           0
    5      -116.299   17:45:31      4           0
    6      -115.829   17:45:31      4           0
    7      -115.714   17:45:31      4           0
    8      -115.686   17:45:31      4           0
    9      -115.679   17:45:31      4           0
    10      -115.678   17:45:31      4           0
    11      -115.677   17:45:32      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -222.684   17:43:32      3           0
    2      -158.781   17:43:33      4           0
    3      -121.774   17:43:33      4           0
    4      -113.324   17:43:33      4           0
    5      -111.771   17:43:33      4           0
    6      -111.357   17:43:33      4           0
    7      -111.249   17:43:33      4           0
    8      -111.223   17:43:33      4           0
    9      -111.218   17:43:33      4           0
    10      -111.217   17:43:33      4           0
    11      -111.216   17:43:33      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -200.245   17:43:38      4           0
    2      -152.635   17:43:38      4           0
    3      -118.714   17:43:38      4           0
    4      -109.475   17:43:38      4           0
    5      -107.975   17:43:38      4           0
    6      -107.604   17:43:38      4           0
    7      -107.502   17:43:38      4           0
    8      -107.473   17:43:38      4           0
    9      -107.465   17:43:38      4           0
    10      -107.463   17:43:38      4           0
    11      -107.462   17:43:38      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -211.734   17:43:43      4           0
    2      -146.529   17:43:43      4           0
    3      -115.665   17:43:43      4           0
    4      -109.365   17:43:43      4           0
    5      -108.383   17:43:43      4           0
    6      -108.153   17:43:43      4           0
    7      -108.091   17:43:43      4           0
    8      -108.074   17:43:44      5           0
    9      -108.069   17:43:44      5           0
    10      -108.068   17:43:44      5           0
    11      -108.067   17:43:44      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -201.13   17:43:48      4           0
    2      -151.04   17:43:48      4           0
    3      -120.555   17:43:48      4           0
    4      -112.379   17:43:48      4           0
    5      -110.616   17:43:48      4           0
    6      -110.004   17:43:49      5           0
    7      -109.76   17:43:49      5           0
    8      -109.66   17:43:49      5           0
    9      -109.619   17:43:49      5           0
    10      -109.603   17:43:49      5           0
    11      -109.597   17:43:49      5           0
    12      -109.594   17:43:49      5           0
    13      -109.594   17:43:49      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -220.049   17:43:53      3           0
    2      -162.065   17:43:54      4           0
    3      -124.097   17:43:54      4           0
    4      -113.198   17:43:54      4           0
    5      -111.22   17:43:54      4           0
    6      -110.747   17:43:54      4           0
    7      -110.642   17:43:54      4           0
    8      -110.622   17:43:54      4           0
    9      -110.619   17:43:54      4           0
    10      -110.618   17:43:54      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -204.834   17:43:59      4           0
    2      -153.496   17:43:59      4           0
    3      -121.225   17:43:59      4           0
    4      -112.091   17:43:59      4           0
    5      -110.216   17:43:59      4           0
    6      -109.645   17:43:59      4           0
    7      -109.454   17:43:59      4           0
    8      -109.389   17:43:59      4           0
    9      -109.367   17:43:59      4           0
    10      -109.36   17:43:59      4           0
    11      -109.357   17:43:59      4           0
    12      -109.357   17:43:59      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -214.819   17:44:4      4           0
    2      -156.424   17:44:4      4           0
    3      -119.932   17:44:4      4           0
    4      -110.378   17:44:4      4           0
    5      -108.94   17:44:4      4           0
    6      -108.663   17:44:4      4           0
    7      -108.61   17:44:4      4           0
    8      -108.6   17:44:4      4           0
    9      -108.598   17:44:4      4           0
    10      -108.597   17:44:4      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -216.798   17:44:9      4           0
    2      -158.403   17:44:9      4           0
    3      -123.171   17:44:9      4           0
    4      -114.383   17:44:9      4           0
    5      -112.81   17:44:9      4           0
    6      -112.396   17:44:9      4           0
    7      -112.282   17:44:9      4           0
    8      -112.252   17:44:9      4           0
    9      -112.244   17:44:9      4           0
    10      -112.243   17:44:9      4           0
    11      -112.242   17:44:9      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -216.888   17:44:14      4           0
    2      -145.665   17:44:14      4           0
    3      -112.797   17:44:14      4           0
    4      -106.648   17:44:14      4           0
    5      -105.867   17:44:14      4           0
    6      -105.716   17:44:14      4           0
    7      -105.684   17:44:14      4           0
    8      -105.677   17:44:14      4           0
    9      -105.676   17:44:14      4           0
    10      -105.675   17:44:14      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -204.151   17:44:19      4           0
    2      -154.336   17:44:19      4           0
    3      -118.126   17:44:19      4           0
    4      -108.862   17:44:19      4           0
    5      -107.418   17:44:19      4           0
    6      -107.088   17:44:19      4           0
    7      -107.009   17:44:19      4           0
    8      -106.989   17:44:19      4           0
    9      -106.985   17:44:19      4           0
    10      -106.984   17:44:19      4           0
    11      -106.984   17:44:19      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -222.721   17:44:24      4           0
    2      -156.643   17:44:24      4           0
    3      -121.353   17:44:24      4           0
    4      -112.586   17:44:24      4           0
    5      -111.004   17:44:24      4           0
    6      -110.622   17:44:24      4           0
    7      -110.532   17:44:24      4           0
    8      -110.512   17:44:24      4           0
    9      -110.508   17:44:24      4           0
    10      -110.507   17:44:24      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -213.443   17:44:29      4           0
    2      -159.061   17:44:29      4           0
    3      -122.044   17:44:29      4           0
    4      -111.95   17:44:29      4           0
    5      -110.115   17:44:29      4           0
    6      -109.642   17:44:29      4           0
    7      -109.519   17:44:29      4           0
    8      -109.489   17:44:29      4           0
    9      -109.482   17:44:29      4           0
    10      -109.481   17:44:29      4           0
    11      -109.48   17:44:29      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -224.84   17:44:34      4           0
    2      -161.757   17:44:34      4           0
    3      -122.3   17:44:34      4           0
    4      -114.256   17:44:34      4           0
    5      -113.159   17:44:34      4           0
    6      -112.909   17:44:34      4           0
    7      -112.846   17:44:34      4           0
    8      -112.829   17:44:34      4           0
    9      -112.825   17:44:34      4           0
    10      -112.824   17:44:34      4           0
    11      -112.823   17:44:34      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -216.015   17:44:39      4           0
    2      -160.519   17:44:39      4           0
    3      -125.062   17:44:39      4           0
    4      -114.53   17:44:39      4           0
    5      -112.327   17:44:39      4           0
    6      -111.676   17:44:39      4           0
    7      -111.485   17:44:39      4           0
    8      -111.434   17:44:39      4           0
    9      -111.422   17:44:39      4           0
    10      -111.419   17:44:39      4           0
    11      -111.418   17:44:39      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -215.473   17:44:44      4           0
    2      -154.298   17:44:44      4           0
    3      -112.882   17:44:44      4           0
    4      -102.575   17:44:44      4           0
    5      -101.694   17:44:44      4           0
    6      -101.63   17:44:44      4           0
    7      -101.627   17:44:44      4           0
    8      -101.626   17:44:44      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -225.862   17:44:49      4           0
    2      -157.503   17:44:49      4           0
    3      -120.677   17:44:49      4           0
    4      -112.363   17:44:49      4           0
    5      -110.834   17:44:49      4           0
    6      -110.47   17:44:49      4           0
    7      -110.394   17:44:49      4           0
    8      -110.381   17:44:49      4           0
    9      -110.379   17:44:49      4           0
    10      -110.379   17:44:49      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -189.407   17:44:54      4           0
    2      -132.082   17:44:54      4           0
    3      -110.288   17:44:54      4           0
    4      -105.566   17:44:54      4           0
    5      -104.734   17:44:54      4           0
    6      -104.512   17:44:54      4           0
    7      -104.443   17:44:54      4           0
    8      -104.421   17:44:54      4           0
    9      -104.413   17:44:54      4           0
    10      -104.41   17:44:54      4           0
    11      -104.409   17:44:54      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -238.69   17:44:58      3           0
    2      -173.137   17:44:59      4           0
    3      -127.218   17:44:59      4           0
    4      -114.646   17:44:59      4           0
    5      -112.851   17:44:59      4           0
    6      -112.602   17:44:59      4           0
    7      -112.577   17:44:59      4           0
    8      -112.575   17:44:59      4           0
    9      -112.575   17:44:59      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -215.71   17:45:3      4           0
    2      -161.67   17:45:3      4           0
    3      -125.963   17:45:3      4           0
    4      -115.77   17:45:3      4           0
    5      -113.717   17:45:4      5           0
    6      -113.122   17:45:4      5           0
    7      -112.948   17:45:4      5           0
    8      -112.902   17:45:4      5           0
    9      -112.891   17:45:4      5           0
    10      -112.888   17:45:4      5           0
    11      -112.888   17:45:4      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -199.331   17:45:8      4           0
    2      -149.883   17:45:8      4           0
    3      -115.276   17:45:8      4           0
    4      -106.572   17:45:9      5           0
    5      -105.411   17:45:9      5           0
    6      -105.167   17:45:9      5           0
    7      -105.109   17:45:9      5           0
    8      -105.094   17:45:9      5           0
    9      -105.09   17:45:9      5           0
    10      -105.089   17:45:9      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -190.766   17:45:13      4           0
    2      -143.12   17:45:13      4           0
    3      -115.645   17:45:13      4           0
    4      -107.977   17:45:14      5           0
    5      -106.372   17:45:14      5           0
    6      -105.891   17:45:14      5           0
    7      -105.733   17:45:14      5           0
    8      -105.68   17:45:14      5           0
    9      -105.663   17:45:14      5           0
    10      -105.657   17:45:14      5           0
    11      -105.655   17:45:14      5           0
    12      -105.655   17:45:14      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -216.184   17:45:18      4           0
    2      -159.49   17:45:18      4           0
    3      -119.865   17:45:18      4           0
    4      -110.645   17:45:19      5           0
    5      -109.541   17:45:19      5           0
    6      -109.349   17:45:19      5           0
    7      -109.313   17:45:19      5           0
    8      -109.306   17:45:19      5           0
    9      -109.305   17:45:19      5           0
    10      -109.305   17:45:19      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -223.169   17:45:23      3           0
    2      -155.793   17:45:23      3           0
    3      -119.353   17:45:24      4           0
    4      -111.334   17:45:24      4           0
    5      -110.246   17:45:24      4           0
    6      -110.052   17:45:24      4           0
    7      -110.018   17:45:24      4           0
    8      -110.012   17:45:24      4           0
    9      -110.011   17:45:24      4           0
    10      -110.01   17:45:24      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -223.117   17:45:28      3           0
    2      -159.338   17:45:29      4           0
    3      -121.335   17:45:29      4           0
    4      -112.765   17:45:29      4           0
    5      -111.36   17:45:29      4           0
    6      -110.998   17:45:29      4           0
    7      -110.898   17:45:29      4           0
    8      -110.87   17:45:29      4           0
    9      -110.863   17:45:29      4           0
    10      -110.861   17:45:29      4           0
    11      -110.861   17:45:29      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -201.965   17:45:33      4           0
    2      -153.139   17:45:33      4           0
    3      -119.917   17:45:33      4           0
    4      -109.935   17:45:33      4           0
    5      -108.094   17:45:34      5           0
    6      -107.603   17:45:34      5           0
    7      -107.461   17:45:34      5           0
    8      -107.419   17:45:34      5           0
    9      -107.407   17:45:34      5           0
    10      -107.404   17:45:34      5           0
    11      -107.403   17:45:34      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -347.58   17:43:36      7           0
    2      -239.963   17:43:36      7           0
    3      -167.887   17:43:37      8           0
    4      -153.795   17:43:37      8           0
    5      -153.344   17:43:37      8           0
    6      -153.314   17:43:37      8           0
    7      -153.312   17:43:37      8           0
    8      -153.311   17:43:37      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -334.323   17:43:45      7           0
    2      -241.07   17:43:45      7           0
    3      -175.855   17:43:45      7           0
    4      -156.366   17:43:45      7           0
    5      -154.522   17:43:45      7           0
    6      -154.385   17:43:46      8           0
    7      -154.376   17:43:46      8           0
    8      -154.375   17:43:46      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -328.501   17:43:53      6           0
    2      -234.667   17:43:54      7           0
    3      -171.981   17:43:54      7           0
    4      -158.395   17:43:54      7           0
    5      -156.985   17:43:54      7           0
    6      -156.703   17:43:54      7           0
    7      -156.635   17:43:54      7           0
    8      -156.618   17:43:55      8           0
    9      -156.613   17:43:55      8           0
    10      -156.612   17:43:55      8           0
    11      -156.612   17:43:55      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -330.99   17:44:3      7           0
    2      -221.786   17:44:3      7           0
    3      -165.653   17:44:3      7           0
    4      -154.798   17:44:3      7           0
    5      -153.85   17:44:3      7           0
    6      -153.725   17:44:3      7           0
    7      -153.706   17:44:4      8           0
    8      -153.703   17:44:4      8           0
    9      -153.703   17:44:4      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -306.16   17:44:11      6           0
    2      -220.918   17:44:12      7           0
    3      -170.527   17:44:12      7           0
    4      -157.152   17:44:12      7           0
    5      -155.616   17:44:12      7           0
    6      -155.346   17:44:12      7           0
    7      -155.288   17:44:12      7           0
    8      -155.275   17:44:12      7           0
    9      -155.272   17:44:13      8           0
    10      -155.271   17:44:13      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -332.045   17:44:20      6           0
    2      -234.309   17:44:21      7           0
    3      -170.956   17:44:21      7           0
    4      -154.899   17:44:21      7           0
    5      -153.601   17:44:21      7           0
    6      -153.486   17:44:21      7           0
    7      -153.475   17:44:21      7           0
    8      -153.474   17:44:22      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -356.531   17:44:29      7           0
    2      -247.109   17:44:29      7           0
    3      -170.597   17:44:30      8           0
    4      -156.024   17:44:30      8           0
    5      -155.752   17:44:30      8           0
    6      -155.739   17:44:30      8           0
    7      -155.738   17:44:30      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -315.851   17:44:37      6           0
    2      -222.163   17:44:38      7           0
    3      -160.164   17:44:38      7           0
    4      -148.706   17:44:38      7           0
    5      -148.224   17:44:38      7           0
    6      -148.189   17:44:38      7           0
    7      -148.186   17:44:38      7           0
    8      -148.186   17:44:39      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -330.108   17:44:46      7           0
    2      -229.746   17:44:46      7           0
    3      -174.569   17:44:47      8           0
    4      -161.855   17:44:47      8           0
    5      -159.891   17:44:47      8           0
    6      -159.361   17:44:47      8           0
    7      -159.193   17:44:47      8           0
    8      -159.137   17:44:47      8           0
    9      -159.119   17:44:48      9           0
    10      -159.112   17:44:48      9           0
    11      -159.11   17:44:48      9           0
    12      -159.109   17:44:48      9           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -332.141   17:44:55      6           0
    2      -228.252   17:44:56      7           0
    3      -173.17   17:44:56      7           0
    4      -160.571   17:44:56      7           0
    5      -158.747   17:44:56      7           0
    6      -158.294   17:44:56      7           0
    7      -158.164   17:44:56      7           0
    8      -158.124   17:44:56      7           0
    9      -158.112   17:44:57      8           0
    10      -158.109   17:44:57      8           0
    11      -158.108   17:44:57      8           0
    12      -158.107   17:44:57      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -320.604   17:45:5      7           0
    2      -222.336   17:45:5      7           0
    3      -166.96   17:45:5      7           0
    4      -154.417   17:45:5      7           0
    5      -153.133   17:45:5      7           0
    6      -152.934   17:45:6      8           0
    7      -152.899   17:45:6      8           0
    8      -152.893   17:45:6      8           0
    9      -152.892   17:45:6      8           0
    10      -152.891   17:45:6      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -323.205   17:45:14      7           0
    2      -238.812   17:45:14      7           0
    3      -172.321   17:45:14      7           0
    4      -155.012   17:45:14      7           0
    5      -154.055   17:45:14      7           0
    6      -153.977   17:45:14      7           0
    7      -153.97   17:45:15      8           0
    8      -153.969   17:45:15      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -337.948   17:45:22      6           0
    2      -238.025   17:45:22      6           0
    3      -176.287   17:45:23      7           0
    4      -161.044   17:45:23      7           0
    5      -159.077   17:45:23      7           0
    6      -158.661   17:45:23      7           0
    7      -158.563   17:45:23      7           0
    8      -158.54   17:45:23      7           0
    9      -158.534   17:45:24      8           0
    10      -158.533   17:45:24      8           0
    11      -158.533   17:45:24      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -348.836   17:45:31      7           0
    2      -236.024   17:45:31      7           0
    3      -168.807   17:45:32      8           0
    4      -155.661   17:45:32      8           0
    5      -155.184   17:45:32      8           0
    6      -155.154   17:45:32      8           0
    7      -155.152   17:45:32      8           0
    8      -155.152   17:45:32      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -331.531   17:45:40      7           0
    2      -232.404   17:45:40      7           0
    3      -170.665   17:45:40      7           0
    4      -156.915   17:45:40      7           0
    5      -155.441   17:45:40      7           0
    6      -155.195   17:45:40      7           0
    7      -155.151   17:45:41      8           0
    8      -155.143   17:45:41      8           0
    9      -155.141   17:45:41      8           0
    10      -155.141   17:45:41      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -322.257   17:45:48      6           0
    2      -225.699   17:45:49      7           0
    3      -167.524   17:45:49      7           0
    4      -154.139   17:45:49      7           0
    5      -153.005   17:45:49      7           0
    6      -152.858   17:45:49      7           0
    7      -152.836   17:45:49      7           0
    8      -152.832   17:45:49      7           0
    9      -152.832   17:45:50      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -338.765   17:45:57      7           0
    2      -234.242   17:45:57      7           0
    3      -173.71   17:45:57      7           0
    4      -159.252   17:45:57      7           0
    5      -157.715   17:45:57      7           0
    6      -157.485   17:45:58      8           0
    7      -157.447   17:45:58      8           0
    8      -157.44   17:45:58      8           0
    9      -157.439   17:45:58      8           0
    10      -157.439   17:45:58      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -339.405   17:46:5      6           0
    2      -239.168   17:46:5      6           0
    3      -176.587   17:46:6      7           0
    4      -160.533   17:46:6      7           0
    5      -158.672   17:46:6      7           0
    6      -158.314   17:46:6      7           0
    7      -158.239   17:46:6      7           0
    8      -158.223   17:46:6      7           0
    9      -158.22   17:46:7      8           0
    10      -158.22   17:46:7      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -330.993   17:46:14      7           0
    2      -219.915   17:46:14      7           0
    3      -164.719   17:46:14      7           0
    4      -154.533   17:46:14      7           0
    5      -153.621   17:46:15      8           0
    6      -153.487   17:46:15      8           0
    7      -153.464   17:46:15      8           0
    8      -153.461   17:46:15      8           0
    9      -153.46   17:46:15      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -338.627   17:46:23      7           0
    2      -238.475   17:46:23      7           0
    3      -172.69   17:46:23      7           0
    4      -157.9   17:46:23      7           0
    5      -156.82   17:46:23      7           0
    6      -156.685   17:46:23      7           0
    7      -156.665   17:46:23      7           0
    8      -156.662   17:46:24      8           0
    9      -156.661   17:46:24      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -326.09   17:46:31      7           0
    2      -228.986   17:46:31      7           0
    3      -168.968   17:46:31      7           0
    4      -157.086   17:46:31      7           0
    5      -155.874   17:46:32      8           0
    6      -155.669   17:46:32      8           0
    7      -155.63   17:46:32      8           0
    8      -155.622   17:46:32      8           0
    9      -155.62   17:46:32      8           0
    10      -155.62   17:46:32      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -358.984   17:46:40      7           0
    2      -227.937   17:46:40      7           0
    3      -165.64   17:46:40      7           0
    4      -154.034   17:46:40      7           0
    5      -153.547   17:46:40      7           0
    6      -153.527   17:46:40      7           0
    7      -153.526   17:46:40      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -337.793   17:46:48      7           0
    2      -231.003   17:46:48      7           0
    3      -168.653   17:46:48      7           0
    4      -155.153   17:46:48      7           0
    5      -154.367   17:46:48      7           0
    6      -154.287   17:46:49      8           0
    7      -154.277   17:46:49      8           0
    8      -154.276   17:46:49      8           0
    9      -154.276   17:46:49      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -323.837   17:46:56      6           0
    2      -229.064   17:46:57      7           0
    3      -172.458   17:46:57      7           0
    4      -158.863   17:46:57      7           0
    5      -157.304   17:46:57      7           0
    6      -157.024   17:46:57      7           0
    7      -156.966   17:46:57      7           0
    8      -156.953   17:46:57      7           0
    9      -156.95   17:46:58      8           0
    10      -156.949   17:46:58      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -332.059   17:47:5      7           0
    2      -236.919   17:47:5      7           0
    3      -174.646   17:47:5      7           0
    4      -157.781   17:47:5      7           0
    5      -156.189   17:47:5      7           0
    6      -155.986   17:47:6      8           0
    7      -155.957   17:47:6      8           0
    8      -155.952   17:47:6      8           0
    9      -155.952   17:47:6      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -326.47   17:43:37      7           0
    2      -233.686   17:43:37      7           0
    3      -174.188   17:43:37      7           0
    4      -157.709   17:43:37      7           0
    5      -155.642   17:43:37      7           0
    6      -155.324   17:43:37      7           0
    7      -155.27   17:43:37      7           0
    8      -155.26   17:43:38      8           0
    9      -155.259   17:43:38      8           0
    10      -155.258   17:43:38      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -331.704   17:43:45      6           0
    2      -233.121   17:43:45      6           0
    3      -171.999   17:43:45      6           0
    4      -155.07   17:43:46      7           0
    5      -153.339   17:43:46      7           0
    6      -153.151   17:43:46      7           0
    7      -153.131   17:43:46      7           0
    8      -153.128   17:43:46      7           0
    9      -153.128   17:43:46      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -353.418   17:43:54      7           0
    2      -231.841   17:43:54      7           0
    3      -169.955   17:43:54      7           0
    4      -157.312   17:43:54      7           0
    5      -156.128   17:43:54      7           0
    6      -155.957   17:43:55      8           0
    7      -155.93   17:43:55      8           0
    8      -155.925   17:43:55      8           0
    9      -155.924   17:43:55      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -319.819   17:44:3      7           0
    2      -236.408   17:44:3      7           0
    3      -172.339   17:44:3      7           0
    4      -155.04   17:44:3      7           0
    5      -153.3   17:44:3      7           0
    6      -153.068   17:44:3      7           0
    7      -153.034   17:44:3      7           0
    8      -153.029   17:44:4      8           0
    9      -153.028   17:44:4      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -312.028   17:44:11      7           0
    2      -224.286   17:44:11      7           0
    3      -170.103   17:44:11      7           0
    4      -155.595   17:44:11      7           0
    5      -153.49   17:44:11      7           0
    6      -153.101   17:44:12      8           0
    7      -153.025   17:44:12      8           0
    8      -153.009   17:44:12      8           0
    9      -153.006   17:44:12      8           0
    10      -153.005   17:44:12      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -314.383   17:44:20      7           0
    2      -229.784   17:44:20      7           0
    3      -169.119   17:44:20      7           0
    4      -153.049   17:44:20      7           0
    5      -151.176   17:44:20      7           0
    6      -150.889   17:44:20      7           0
    7      -150.841   17:44:20      7           0
    8      -150.833   17:44:21      8           0
    9      -150.832   17:44:21      8           0
    10      -150.831   17:44:21      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -321.766   17:44:28      6           0
    2      -227.865   17:44:28      6           0
    3      -173.751   17:44:29      7           0
    4      -158.33   17:44:29      7           0
    5      -155.765   17:44:29      7           0
    6      -155.254   17:44:29      7           0
    7      -155.152   17:44:29      7           0
    8      -155.133   17:44:29      7           0
    9      -155.129   17:44:30      8           0
    10      -155.128   17:44:30      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -337.238   17:44:37      7           0
    2      -244.337   17:44:37      7           0
    3      -181.314   17:44:37      7           0
    4      -162.349   17:44:37      7           0
    5      -159.127   17:44:38      8           0
    6      -158.482   17:44:38      8           0
    7      -158.362   17:44:38      8           0
    8      -158.341   17:44:38      8           0
    9      -158.337   17:44:38      8           0
    10      -158.337   17:44:38      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -336.061   17:44:46      7           0
    2      -236.873   17:44:46      7           0
    3      -172.421   17:44:46      7           0
    4      -155.502   17:44:46      7           0
    5      -154.016   17:44:46      7           0
    6      -153.845   17:44:46      7           0
    7      -153.824   17:44:47      8           0
    8      -153.821   17:44:47      8           0
    9      -153.821   17:44:47      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -326.886   17:44:54      7           0
    2      -230.312   17:44:54      7           0
    3      -167.278   17:44:54      7           0
    4      -152.865   17:44:55      8           0
    5      -151.881   17:44:55      8           0
    6      -151.799   17:44:55      8           0
    7      -151.791   17:44:55      8           0
    8      -151.791   17:44:55      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -337.692   17:45:2      6           0
    2      -237.909   17:45:3      7           0
    3      -175.605   17:45:3      7           0
    4      -159.037   17:45:3      7           0
    5      -156.835   17:45:3      7           0
    6      -156.463   17:45:3      7           0
    7      -156.401   17:45:3      7           0
    8      -156.391   17:45:3      7           0
    9      -156.389   17:45:4      8           0
    10      -156.389   17:45:4      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -322.081   17:45:11      7           0
    2      -205.798   17:45:11      7           0
    3      -160.516   17:45:11      7           0
    4      -151.357   17:45:12      8           0
    5      -150.185   17:45:12      8           0
    6      -149.988   17:45:12      8           0
    7      -149.952   17:45:12      8           0
    8      -149.945   17:45:12      8           0
    9      -149.944   17:45:12      8           0
    10      -149.944   17:45:12      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -352.145   17:45:20      7           0
    2      -253.435   17:45:20      7           0
    3      -178.475   17:45:20      7           0
    4      -159.416   17:45:20      7           0
    5      -158.249   17:45:20      7           0
    6      -158.115   17:45:20      7           0
    7      -158.095   17:45:21      8           0
    8      -158.091   17:45:21      8           0
    9      -158.091   17:45:21      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -317.61   17:45:28      7           0
    2      -233.213   17:45:28      7           0
    3      -170.407   17:45:28      7           0
    4      -153.687   17:45:28      7           0
    5      -152.101   17:45:29      8           0
    6      -151.919   17:45:29      8           0
    7      -151.896   17:45:29      8           0
    8      -151.893   17:45:29      8           0
    9      -151.893   17:45:29      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -311.171   17:45:36      6           0
    2      -235.206   17:45:37      7           0
    3      -176.29   17:45:37      7           0
    4      -157.913   17:45:37      7           0
    5      -154.733   17:45:37      7           0
    6      -154.073   17:45:37      7           0
    7      -153.943   17:45:37      7           0
    8      -153.918   17:45:37      7           0
    9      -153.914   17:45:38      8           0
    10      -153.913   17:45:38      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -320.207   17:45:45      7           0
    2      -232.588   17:45:45      7           0
    3      -168.832   17:45:45      7           0
    4      -152.16   17:45:45      7           0
    5      -151.01   17:45:45      7           0
    6      -150.918   17:45:46      8           0
    7      -150.91   17:45:46      8           0
    8      -150.91   17:45:46      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -327.728   17:45:53      7           0
    2      -246.166   17:45:53      7           0
    3      -178.394   17:45:53      7           0
    4      -156.146   17:45:53      7           0
    5      -153.645   17:45:53      7           0
    6      -153.382   17:45:54      8           0
    7      -153.356   17:45:54      8           0
    8      -153.354   17:45:54      8           0
    9      -153.354   17:45:54      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -320.606   17:46:1      6           0
    2      -223.683   17:46:1      6           0
    3      -169.048   17:46:1      6           0
    4      -154.97   17:46:1      6           0
    5      -153.14   17:46:2      7           0
    6      -152.855   17:46:2      7           0
    7      -152.809   17:46:2      7           0
    8      -152.802   17:46:2      7           0
    9      -152.8   17:46:2      7           0
    10      -152.8   17:46:2      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -337.539   17:46:9      6           0
    2      -235.751   17:46:10      7           0
    3      -175.282   17:46:10      7           0
    4      -159.471   17:46:10      7           0
    5      -157.302   17:46:10      7           0
    6      -156.909   17:46:10      7           0
    7      -156.836   17:46:10      7           0
    8      -156.823   17:46:10      7           0
    9      -156.821   17:46:11      8           0
    10      -156.82   17:46:11      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -347.57   17:46:18      7           0
    2      -222.193   17:46:18      7           0
    3      -169.713   17:46:18      7           0
    4      -158.076   17:46:18      7           0
    5      -156.491   17:46:18      7           0
    6      -156.218   17:46:18      7           0
    7      -156.169   17:46:18      7           0
    8      -156.161   17:46:19      8           0
    9      -156.159   17:46:19      8           0
    10      -156.159   17:46:19      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -302.932   17:46:26      6           0
    2      -208.557   17:46:26      6           0
    3      -159.472   17:46:26      6           0
    4      -148.306   17:46:26      6           0
    5      -147.069   17:46:27      7           0
    6      -146.896   17:46:27      7           0
    7      -146.871   17:46:27      7           0
    8      -146.867   17:46:27      7           0
    9      -146.866   17:46:27      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -340.144   17:46:34      6           0
    2      -240.59   17:46:34      6           0
    3      -175.292   17:46:34      6           0
    4      -158.407   17:46:34      6           0
    5      -156.155   17:46:35      7           0
    6      -155.769   17:46:35      7           0
    7      -155.707   17:46:35      7           0
    8      -155.697   17:46:35      7           0
    9      -155.696   17:46:35      7           0
    10      -155.696   17:46:35      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -332.129   17:46:42      6           0
    2      -232.019   17:46:43      7           0
    3      -172.266   17:46:43      7           0
    4      -158.328   17:46:43      7           0
    5      -156.594   17:46:43      7           0
    6      -156.292   17:46:43      7           0
    7      -156.233   17:46:43      7           0
    8      -156.221   17:46:43      7           0
    9      -156.218   17:46:44      8           0
    10      -156.217   17:46:44      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -337.326   17:46:51      7           0
    2      -242.248   17:46:51      7           0
    3      -174.244   17:46:51      7           0
    4      -156.799   17:46:51      7           0
    5      -155.319   17:46:51      7           0
    6      -155.135   17:46:51      7           0
    7      -155.109   17:46:52      8           0
    8      -155.106   17:46:52      8           0
    9      -155.105   17:46:52      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -324.728   17:46:59      7           0
    2      -241.579   17:46:59      7           0
    3      -176.797   17:46:59      7           0
    4      -156.345   17:46:59      7           0
    5      -154.477   17:46:59      7           0
    6      -154.29   17:46:59      7           0
    7      -154.269   17:46:59      7           0
    8      -154.266   17:47:0      8           0
    9      -154.266   17:47:0      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -263.042   17:43:34      4           0
    2      -174.813   17:43:34      4           0
    3      -125.105   17:43:34      4           0
    4      -113.366   17:43:34      4           0
    5      -113.132   17:43:35      5           0
    6      -113.132   17:43:35      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -223.382   17:43:39      4           0
    2      -163.106   17:43:39      4           0
    3      -126.824   17:43:39      4           0
    4      -117.43   17:43:39      4           0
    5      -116.015   17:43:39      4           0
    6      -115.746   17:43:39      4           0
    7      -115.692   17:43:40      5           0
    8      -115.681   17:43:40      5           0
    9      -115.679   17:43:40      5           0
    10      -115.678   17:43:40      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -226.767   17:43:44      4           0
    2      -156.394   17:43:44      4           0
    3      -117.969   17:43:45      5           0
    4      -110.434   17:43:45      5           0
    5      -109.805   17:43:45      5           0
    6      -109.738   17:43:45      5           0
    7      -109.73   17:43:45      5           0
    8      -109.729   17:43:45      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -257.649   17:43:50      4           0
    2      -183.22   17:43:50      4           0
    3      -135.905   17:43:50      4           0
    4      -121.77   17:43:50      4           0
    5      -119.764   17:43:50      4           0
    6      -119.48   17:43:50      4           0
    7      -119.448   17:43:50      4           0
    8      -119.445   17:43:50      4           0
    9      -119.445   17:43:50      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -263.468   17:43:55      4           0
    2      -186.463   17:43:55      4           0
    3      -133.319   17:43:55      4           0
    4      -120.557   17:43:55      4           0
    5      -119.584   17:43:55      4           0
    6      -119.485   17:43:55      4           0
    7      -119.474   17:43:55      4           0
    8      -119.472   17:43:55      4           0
    9      -119.472   17:43:55      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -259.002   17:44:0      4           0
    2      -173.595   17:44:0      4           0
    3      -126.821   17:44:0      4           0
    4      -116.991   17:44:0      4           0
    5      -116.366   17:44:0      4           0
    6      -116.325   17:44:0      4           0
    7      -116.323   17:44:0      4           0
    8      -116.323   17:44:0      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -246.854   17:44:5      4           0
    2      -175.411   17:44:5      4           0
    3      -130.033   17:44:5      4           0
    4      -119.101   17:44:5      4           0
    5      -118.014   17:44:5      4           0
    6      -117.878   17:44:5      4           0
    7      -117.86   17:44:5      4           0
    8      -117.858   17:44:5      4           0
    9      -117.857   17:44:5      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -256.862   17:44:10      4           0
    2      -172.37   17:44:10      4           0
    3      -126.931   17:44:10      4           0
    4      -115.674   17:44:10      4           0
    5      -114.887   17:44:10      4           0
    6      -114.855   17:44:10      4           0
    7      -114.854   17:44:10      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -208.783   17:44:14      3           0
    2      -143.646   17:44:15      4           0
    3      -116.187   17:44:15      4           0
    4      -110.658   17:44:15      4           0
    5      -109.832   17:44:15      4           0
    6      -109.653   17:44:15      4           0
    7      -109.609   17:44:15      4           0
    8      -109.597   17:44:15      4           0
    9      -109.594   17:44:15      4           0
    10      -109.593   17:44:15      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -262.712   17:44:19      3           0
    2      -178.729   17:44:20      4           0
    3      -130.218   17:44:20      4           0
    4      -120.583   17:44:20      4           0
    5      -119.872   17:44:20      4           0
    6      -119.788   17:44:20      4           0
    7      -119.776   17:44:20      4           0
    8      -119.775   17:44:20      4           0
    9      -119.774   17:44:20      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -254.134   17:44:24      4           0
    2      -184.59   17:44:24      4           0
    3      -137.476   17:44:24      4           0
    4      -123.168   17:44:24      4           0
    5      -120.954   17:44:24      4           0
    6      -120.569   17:44:25      5           0
    7      -120.503   17:44:25      5           0
    8      -120.493   17:44:25      5           0
    9      -120.491   17:44:25      5           0
    10      -120.491   17:44:25      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -234.121   17:44:29      4           0
    2      -166.72   17:44:29      4           0
    3      -127.015   17:44:29      4           0
    4      -117.115   17:44:30      5           0
    5      -115.738   17:44:30      5           0
    6      -115.492   17:44:30      5           0
    7      -115.444   17:44:30      5           0
    8      -115.435   17:44:30      5           0
    9      -115.433   17:44:30      5           0
    10      -115.432   17:44:30      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -239.439   17:44:34      4           0
    2      -161.55   17:44:34      4           0
    3      -124.233   17:44:34      4           0
    4      -116.608   17:44:34      4           0
    5      -115.712   17:44:35      5           0
    6      -115.568   17:44:35      5           0
    7      -115.543   17:44:35      5           0
    8      -115.539   17:44:35      5           0
    9      -115.538   17:44:35      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -247.313   17:44:39      4           0
    2      -166.507   17:44:39      4           0
    3      -117.523   17:44:39      4           0
    4      -110.375   17:44:39      4           0
    5      -110.294   17:44:40      5           0
    6      -110.292   17:44:40      5           0
    7      -110.292   17:44:40      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -252.846   17:44:44      4           0
    2      -173.574   17:44:44      4           0
    3      -129.75   17:44:44      4           0
    4      -118.087   17:44:44      4           0
    5      -116.895   17:44:44      4           0
    6      -116.81   17:44:44      4           0
    7      -116.806   17:44:45      5           0
    8      -116.805   17:44:45      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -239.49   17:44:49      4           0
    2      -177.255   17:44:49      4           0
    3      -130.194   17:44:49      4           0
    4      -116.043   17:44:49      4           0
    5      -114.725   17:44:49      4           0
    6      -114.637   17:44:49      4           0
    7      -114.631   17:44:49      4           0
    8      -114.631   17:44:49      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -257.084   17:44:54      4           0
    2      -174.133   17:44:54      4           0
    3      -128.518   17:44:54      4           0
    4      -119.441   17:44:54      4           0
    5      -118.558   17:44:54      4           0
    6      -118.448   17:44:54      4           0
    7      -118.435   17:44:54      4           0
    8      -118.433   17:44:55      5           0
    9      -118.433   17:44:55      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -246.573   17:44:59      4           0
    2      -163.577   17:44:59      4           0
    3      -125.924   17:44:59      4           0
    4      -117.245   17:44:59      4           0
    5      -116.229   17:44:59      4           0
    6      -116.094   17:44:59      4           0
    7      -116.075   17:44:59      4           0
    8      -116.073   17:44:59      4           0
    9      -116.072   17:44:59      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -228.42   17:45:4      4           0
    2      -167.095   17:45:4      4           0
    3      -131.788   17:45:4      4           0
    4      -121.572   17:45:4      4           0
    5      -119.638   17:45:4      4           0
    6      -119.139   17:45:4      4           0
    7      -118.995   17:45:4      4           0
    8      -118.952   17:45:4      4           0
    9      -118.938   17:45:4      4           0
    10      -118.934   17:45:4      4           0
    11      -118.933   17:45:4      4           0
    12      -118.933   17:45:4      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -251.018   17:45:9      4           0
    2      -169.355   17:45:9      4           0
    3      -122.62   17:45:9      4           0
    4      -113.879   17:45:9      4           0
    5      -113.457   17:45:9      4           0
    6      -113.429   17:45:9      4           0
    7      -113.427   17:45:9      4           0
    8      -113.427   17:45:9      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -246.369   17:45:13      3           0
    2      -169.15   17:45:14      4           0
    3      -127.872   17:45:14      4           0
    4      -117.64   17:45:14      4           0
    5      -116.608   17:45:14      4           0
    6      -116.499   17:45:14      4           0
    7      -116.488   17:45:14      4           0
    8      -116.486   17:45:14      4           0
    9      -116.486   17:45:14      4           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -240.558   17:45:18      4           0
    2      -159.397   17:45:18      4           0
    3      -120.04   17:45:18      4           0
    4      -112.676   17:45:18      4           0
    5      -112.053   17:45:18      4           0
    6      -111.985   17:45:19      5           0
    7      -111.977   17:45:19      5           0
    8      -111.976   17:45:19      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -254.931   17:45:23      4           0
    2      -172.289   17:45:23      4           0
    3      -129.118   17:45:23      4           0
    4      -119.53   17:45:23      4           0
    5      -118.337   17:45:23      4           0
    6      -118.161   17:45:24      5           0
    7      -118.136   17:45:24      5           0
    8      -118.132   17:45:24      5           0
    9      -118.131   17:45:24      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -250.301   17:45:28      4           0
    2      -174.395   17:45:28      4           0
    3      -126.917   17:45:28      4           0
    4      -115.345   17:45:28      4           0
    5      -114.599   17:45:29      5           0
    6      -114.561   17:45:29      5           0
    7      -114.559   17:45:29      5           0
    8      -114.559   17:45:29      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -263.492   17:45:33      4           0
    2      -181.423   17:45:33      4           0
    3      -134.477   17:45:33      4           0
    4      -123.031   17:45:33      4           0
    5      -121.393   17:45:33      4           0
    6      -121.075   17:45:33      4           0
    7      -121.015   17:45:33      4           0
    8      -121.004   17:45:33      4           0
    9      -121.003   17:45:34      5           0
    10      -121.002   17:45:34      5           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -330.072   17:43:38      7           0
    2      -239.568   17:43:38      7           0
    3      -166.027   17:43:38      7           0
    4      -147.708   17:43:38      7           0
    5      -147.153   17:43:38      7           0
    6      -147.135   17:43:38      7           0
    7      -147.134   17:43:38      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -330.527   17:43:46      7           0
    2      -243.209   17:43:46      7           0
    3      -167.931   17:43:46      7           0
    4      -146.966   17:43:46      7           0
    5      -146.255   17:43:46      7           0
    6      -146.231   17:43:47      8           0
    7      -146.23   17:43:47      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -338.427   17:43:54      7           0
    2      -235.874   17:43:54      7           0
    3      -160.207   17:43:54      7           0
    4      -144.101   17:43:54      7           0
    5      -143.859   17:43:55      8           0
    6      -143.856   17:43:55      8           0
    7      -143.856   17:43:55      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -321.882   17:44:2      6           0
    2      -220.324   17:44:2      6           0
    3      -156.634   17:44:2      6           0
    4      -142.278   17:44:3      7           0
    5      -141.755   17:44:3      7           0
    6      -141.738   17:44:3      7           0
    7      -141.737   17:44:3      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -310.408   17:44:10      6           0
    2      -217.842   17:44:10      6           0
    3      -165.633   17:44:10      6           0
    4      -151.392   17:44:11      7           0
    5      -149.305   17:44:11      7           0
    6      -148.9   17:44:11      7           0
    7      -148.82   17:44:11      7           0
    8      -148.804   17:44:11      7           0
    9      -148.801   17:44:11      7           0
    10      -148.801   17:44:12      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -312.625   17:44:19      7           0
    2      -237.875   17:44:19      7           0
    3      -170.907   17:44:19      7           0
    4      -148.983   17:44:19      7           0
    5      -147.026   17:44:19      7           0
    6      -146.865   17:44:20      8           0
    7      -146.853   17:44:20      8           0
    8      -146.852   17:44:20      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -338.407   17:44:27      6           0
    2      -232.366   17:44:27      6           0
    3      -162.793   17:44:27      6           0
    4      -148.019   17:44:28      7           0
    5      -147.401   17:44:28      7           0
    6      -147.378   17:44:28      7           0
    7      -147.377   17:44:28      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -335.785   17:44:35      6           0
    2      -233.506   17:44:35      6           0
    3      -164.975   17:44:35      6           0
    4      -148.389   17:44:36      7           0
    5      -147.665   17:44:36      7           0
    6      -147.632   17:44:36      7           0
    7      -147.631   17:44:36      7           0
    8      -147.631   17:44:36      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -322.807   17:44:44      7           0
    2      -239.865   17:44:44      7           0
    3      -163.592   17:44:44      7           0
    4      -143.252   17:44:44      7           0
    5      -142.882   17:44:44      7           0
    6      -142.874   17:44:44      7           0
    7      -142.874   17:44:44      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -322.553   17:44:52      7           0
    2      -222.252   17:44:52      7           0
    3      -159.147   17:44:52      7           0
    4      -145.4   17:44:52      7           0
    5      -144.667   17:44:52      7           0
    6      -144.601   17:44:52      7           0
    7      -144.595   17:44:53      8           0
    8      -144.594   17:44:53      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -330.491   17:45:0      7           0
    2      -216.817   17:45:0      7           0
    3      -153.946   17:45:0      7           0
    4      -142.99   17:45:1      8           0
    5      -142.814   17:45:1      8           0
    6      -142.809   17:45:1      8           0
    7      -142.809   17:45:1      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -324.266   17:45:8      6           0
    2      -226.991   17:45:8      6           0
    3      -162.345   17:45:9      7           0
    4      -146.718   17:45:9      7           0
    5      -145.814   17:45:9      7           0
    6      -145.764   17:45:9      7           0
    7      -145.762   17:45:9      7           0
    8      -145.762   17:45:9      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -326.643   17:45:17      7           0
    2      -235.841   17:45:17      7           0
    3      -165.277   17:45:17      7           0
    4      -147.759   17:45:17      7           0
    5      -146.897   17:45:17      7           0
    6      -146.842   17:45:17      7           0
    7      -146.839   17:45:17      7           0
    8      -146.838   17:45:18      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -335.138   17:45:25      7           0
    2      -233.062   17:45:25      7           0
    3      -159.186   17:45:25      7           0
    4      -143.238   17:45:25      7           0
    5      -142.855   17:45:25      7           0
    6      -142.849   17:45:26      8           0
    7      -142.849   17:45:26      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -337.162   17:45:33      7           0
    2      -240.717   17:45:33      7           0
    3      -170.538   17:45:33      7           0
    4      -150.689   17:45:34      8           0
    5      -149.654   17:45:34      8           0
    6      -149.601   17:45:34      8           0
    7      -149.599   17:45:34      8           0
    8      -149.599   17:45:34      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -338.489   17:45:41      6           0
    2      -234.013   17:45:41      6           0
    3      -168.203   17:45:42      7           0
    4      -150.579   17:45:42      7           0
    5      -149.397   17:45:42      7           0
    6      -149.323   17:45:42      7           0
    7      -149.319   17:45:42      7           0
    8      -149.319   17:45:42      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -313.129   17:45:49      6           0
    2      -232.664   17:45:49      6           0
    3      -163.696   17:45:49      6           0
    4      -144.216   17:45:50      7           0
    5      -143.119   17:45:50      7           0
    6      -143.063   17:45:50      7           0
    7      -143.06   17:45:50      7           0
    8      -143.06   17:45:50      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -325.34   17:45:57      6           0
    2      -223.777   17:45:57      6           0
    3      -158.601   17:45:57      6           0
    4      -146.713   17:45:57      6           0
    5      -146.364   17:45:58      7           0
    6      -146.341   17:45:58      7           0
    7      -146.339   17:45:58      7           0
    8      -146.339   17:45:58      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -322.702   17:46:5      6           0
    2      -222.562   17:46:5      6           0
    3      -158.397   17:46:5      6           0
    4      -143.39   17:46:6      7           0
    5      -142.424   17:46:6      7           0
    6      -142.366   17:46:6      7           0
    7      -142.363   17:46:6      7           0
    8      -142.363   17:46:6      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -330.59   17:46:13      6           0
    2      -235.919   17:46:13      6           0
    3      -163.212   17:46:13      6           0
    4      -145.792   17:46:13      6           0
    5      -145.445   17:46:14      7           0
    6      -145.438   17:46:14      7           0
    7      -145.438   17:46:14      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -344.548   17:46:21      6           0
    2      -223.419   17:46:21      6           0
    3      -153.449   17:46:21      6           0
    4      -143.379   17:46:21      6           0
    5      -143.305   17:46:22      7           0
    6      -143.304   17:46:22      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -306.41   17:46:29      7           0
    2      -219.426   17:46:29      7           0
    3      -161.355   17:46:29      7           0
    4      -145.383   17:46:29      7           0
    5      -144.126   17:46:29      7           0
    6      -144.012   17:46:29      7           0
    7      -144.001   17:46:30      8           0
    8      -144   17:46:30      8           0
    9      -143.999   17:46:30      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -326.979   17:46:37      7           0
    2      -227.775   17:46:37      7           0
    3      -164.227   17:46:37      7           0
    4      -149.148   17:46:37      7           0
    5      -148.238   17:46:37      7           0
    6      -148.143   17:46:38      8           0
    7      -148.132   17:46:38      8           0
    8      -148.131   17:46:38      8           0
    9      -148.131   17:46:38      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -324.753   17:46:45      6           0
    2      -230.414   17:46:45      6           0
    3      -159.653   17:46:45      6           0
    4      -142.863   17:46:45      6           0
    5      -142.185   17:46:46      7           0
    6      -142.162   17:46:46      7           0
    7      -142.162   17:46:46      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -334.471   17:46:53      7           0
    2      -236.349   17:46:53      7           0
    3      -165.073   17:46:53      7           0
    4      -148.915   17:46:53      7           0
    5      -148.195   17:46:53      7           0
    6      -148.159   17:46:53      7           0
    7      -148.157   17:46:54      8           0
    8      -148.157   17:46:54      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -369.17   17:43:38      6           0
    2      -223.098   17:43:38      6           0
    3      -166.59   17:43:38      6           0
    4      -155.067   17:43:39      7           0
    5      -154.156   17:43:39      7           0
    6      -154.101   17:43:39      7           0
    7      -154.098   17:43:39      7           0
    8      -154.098   17:43:39      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -353.794   17:43:47      7           0
    2      -224.302   17:43:47      7           0
    3      -162.108   17:43:47      7           0
    4      -149.84   17:43:47      7           0
    5      -149.277   17:43:47      7           0
    6      -149.249   17:43:47      7           0
    7      -149.247   17:43:47      7           0
    8      -149.247   17:43:48      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -344.711   17:43:55      7           0
    2      -216.207   17:43:55      7           0
    3      -160.893   17:43:55      7           0
    4      -149.444   17:43:55      7           0
    5      -148.579   17:43:56      8           0
    6      -148.517   17:43:56      8           0
    7      -148.513   17:43:56      8           0
    8      -148.513   17:43:56      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -342.982   17:44:3      6           0
    2      -230.952   17:44:4      7           0
    3      -162.696   17:44:4      7           0
    4      -147.192   17:44:4      7           0
    5      -146.765   17:44:4      7           0
    6      -146.761   17:44:4      7           0
    7      -146.761   17:44:4      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -351.57   17:44:12      7           0
    2      -224.684   17:44:12      7           0
    3      -162.565   17:44:12      7           0
    4      -151.817   17:44:12      7           0
    5      -151.169   17:44:12      7           0
    6      -151.113   17:44:12      7           0
    7      -151.108   17:44:12      7           0
    8      -151.108   17:44:13      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -343.164   17:44:20      7           0
    2      -217.009   17:44:20      7           0
    3      -161.798   17:44:20      7           0
    4      -150.502   17:44:20      7           0
    5      -149.621   17:44:21      8           0
    6      -149.55   17:44:21      8           0
    7      -149.545   17:44:21      8           0
    8      -149.545   17:44:21      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -356.949   17:44:28      6           0
    2      -226.729   17:44:28      6           0
    3      -164.033   17:44:29      7           0
    4      -152.09   17:44:29      7           0
    5      -151.511   17:44:29      7           0
    6      -151.471   17:44:29      7           0
    7      -151.468   17:44:29      7           0
    8      -151.468   17:44:29      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -339.68   17:44:36      6           0
    2      -217.106   17:44:37      7           0
    3      -159.919   17:44:37      7           0
    4      -149.866   17:44:37      7           0
    5      -149.13   17:44:37      7           0
    6      -149.047   17:44:37      7           0
    7      -149.037   17:44:37      7           0
    8      -149.035   17:44:37      7           0
    9      -149.035   17:44:38      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -358.516   17:44:45      7           0
    2      -233.251   17:44:45      7           0
    3      -162.741   17:44:45      7           0
    4      -148.636   17:44:45      7           0
    5      -148.477   17:44:46      8           0
    6      -148.477   17:44:46      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -360.094   17:44:53      7           0
    2      -218.794   17:44:53      7           0
    3      -159.518   17:44:53      7           0
    4      -148.92   17:44:53      7           0
    5      -148.635   17:44:53      7           0
    6      -148.631   17:44:54      8           0
    7      -148.631   17:44:54      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -334.692   17:45:1      7           0
    2      -220.782   17:45:1      7           0
    3      -157.693   17:45:1      7           0
    4      -145.411   17:45:1      7           0
    5      -144.804   17:45:2      8           0
    6      -144.772   17:45:2      8           0
    7      -144.77   17:45:2      8           0
    8      -144.77   17:45:2      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -343.636   17:45:9      6           0
    2      -231.899   17:45:10      7           0
    3      -168.188   17:45:10      7           0
    4      -153.436   17:45:10      7           0
    5      -152.012   17:45:10      7           0
    6      -151.877   17:45:10      7           0
    7      -151.865   17:45:10      7           0
    8      -151.864   17:45:10      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -360.829   17:45:18      7           0
    2      -217.726   17:45:18      7           0
    3      -160.309   17:45:18      7           0
    4      -149.746   17:45:18      7           0
    5      -149.227   17:45:18      7           0
    6      -149.208   17:45:19      8           0
    7      -149.207   17:45:19      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -362.053   17:45:26      7           0
    2      -227.191   17:45:26      7           0
    3      -163.057   17:45:26      7           0
    4      -151.448   17:45:27      8           0
    5      -151.045   17:45:27      8           0
    6      -151.034   17:45:27      8           0
    7      -151.034   17:45:27      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -357.725   17:45:34      6           0
    2      -216.377   17:45:34      6           0
    3      -163.238   17:45:35      7           0
    4      -152.188   17:45:35      7           0
    5      -151.525   17:45:35      7           0
    6      -151.49   17:45:35      7           0
    7      -151.488   17:45:35      7           0
    8      -151.488   17:45:35      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -327.284   17:45:42      6           0
    2      -219.166   17:45:42      6           0
    3      -158.823   17:45:43      7           0
    4      -147.032   17:45:43      7           0
    5      -146.225   17:45:43      7           0
    6      -146.148   17:45:43      7           0
    7      -146.141   17:45:43      7           0
    8      -146.14   17:45:43      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -354.179   17:45:50      6           0
    2      -228.16   17:45:50      6           0
    3      -167.795   17:45:51      7           0
    4      -152.663   17:45:51      7           0
    5      -151.46   17:45:51      7           0
    6      -151.418   17:45:51      7           0
    7      -151.418   17:45:51      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -353.703   17:45:58      6           0
    2      -231.317   17:45:58      6           0
    3      -166.912   17:45:58      6           0
    4      -151.524   17:45:58      6           0
    5      -150.702   17:45:59      7           0
    6      -150.681   17:45:59      7           0
    7      -150.681   17:45:59      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -357.283   17:46:6      6           0
    2      -229.204   17:46:6      6           0
    3      -161.914   17:46:6      6           0
    4      -151.005   17:46:6      6           0
    5      -150.637   17:46:7      7           0
    6      -150.619   17:46:7      7           0
    7      -150.618   17:46:7      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -370.501   17:46:14      7           0
    2      -226.725   17:46:14      7           0
    3      -162.477   17:46:14      7           0
    4      -152.095   17:46:14      7           0
    5      -151.638   17:46:14      7           0
    6      -151.618   17:46:14      7           0
    7      -151.617   17:46:15      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -348.397   17:46:22      7           0
    2      -215.828   17:46:22      7           0
    3      -160.962   17:46:22      7           0
    4      -150.636   17:46:22      7           0
    5      -149.969   17:46:22      7           0
    6      -149.924   17:46:22      7           0
    7      -149.921   17:46:23      8           0
    8      -149.92   17:46:23      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -363.576   17:46:30      7           0
    2      -231.839   17:46:30      7           0
    3      -160.586   17:46:30      7           0
    4      -148.588   17:46:30      7           0
    5      -148.389   17:46:30      7           0
    6      -148.388   17:46:30      7           0
    7      -148.388   17:46:30      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -350.246   17:46:38      7           0
    2      -228.187   17:46:38      7           0
    3      -162.591   17:46:38      7           0
    4      -148.87   17:46:38      7           0
    5      -148.36   17:46:38      7           0
    6      -148.349   17:46:38      7           0
    7      -148.349   17:46:38      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -335.078   17:46:45      6           0
    2      -234.167   17:46:46      7           0
    3      -168.755   17:46:46      7           0
    4      -153.469   17:46:46      7           0
    5      -151.726   17:46:46      7           0
    6      -151.464   17:46:46      7           0
    7      -151.427   17:46:46      7           0
    8      -151.422   17:46:46      7           0
    9      -151.421   17:46:47      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -356.987   17:46:53      6           0
    2      -205.149   17:46:54      7           0
    3      -157.856   17:46:54      7           0
    4      -149.696   17:46:54      7           0
    5      -149.24   17:46:54      7           0
    6      -149.21   17:46:54      7           0
    7      -149.208   17:46:54      7           0
    8      -149.207   17:46:54      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -320.52   17:43:39      7           0
    2      -220.791   17:43:39      7           0
    3      -162.892   17:43:39      7           0
    4      -150.701   17:43:40      8           0
    5      -150.091   17:43:40      8           0
    6      -150.048   17:43:40      8           0
    7      -150.045   17:43:40      8           0
    8      -150.045   17:43:40      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -310.606   17:43:48      7           0
    2      -228.069   17:43:48      7           0
    3      -165.507   17:43:48      7           0
    4      -149.365   17:43:48      7           0
    5      -148.687   17:43:48      7           0
    6      -148.648   17:43:49      8           0
    7      -148.645   17:43:49      8           0
    8      -148.645   17:43:49      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -317.989   17:43:56      6           0
    2      -208.64   17:43:57      7           0
    3      -157.296   17:43:57      7           0
    4      -149.234   17:43:57      7           0
    5      -148.972   17:43:57      7           0
    6      -148.956   17:43:57      7           0
    7      -148.954   17:43:57      7           0
    8      -148.954   17:43:58      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -322.202   17:44:5      7           0
    2      -221.677   17:44:5      7           0
    3      -164.363   17:44:5      7           0
    4      -153.673   17:44:6      8           0
    5      -153.029   17:44:6      8           0
    6      -152.949   17:44:6      8           0
    7      -152.937   17:44:6      8           0
    8      -152.935   17:44:6      8           0
    9      -152.935   17:44:6      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -328.424   17:44:14      7           0
    2      -244.97   17:44:14      7           0
    3      -173.579   17:44:14      7           0
    4      -154.441   17:44:14      7           0
    5      -153.831   17:44:14      7           0
    6      -153.801   17:44:15      8           0
    7      -153.799   17:44:15      8           0
    8      -153.799   17:44:15      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -338.346   17:44:23      7           0
    2      -248.181   17:44:23      7           0
    3      -177.664   17:44:23      7           0
    4      -156.006   17:44:23      7           0
    5      -154.787   17:44:23      7           0
    6      -154.711   17:44:23      7           0
    7      -154.706   17:44:23      7           0
    8      -154.705   17:44:24      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -309.722   17:44:31      7           0
    2      -232.788   17:44:31      7           0
    3      -169.952   17:44:31      7           0
    4      -153.727   17:44:32      8           0
    5      -152.831   17:44:32      8           0
    6      -152.741   17:44:32      8           0
    7      -152.73   17:44:32      8           0
    8      -152.728   17:44:32      8           0
    9      -152.728   17:44:32      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -337.29   17:44:40      7           0
    2      -240.576   17:44:40      7           0
    3      -171.649   17:44:40      7           0
    4      -155.223   17:44:40      7           0
    5      -154.714   17:44:40      7           0
    6      -154.677   17:44:41      8           0
    7      -154.674   17:44:41      8           0
    8      -154.673   17:44:41      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -306.015   17:44:48      6           0
    2      -211.939   17:44:49      7           0
    3      -156.258   17:44:49      7           0
    4      -146.318   17:44:49      7           0
    5      -146.094   17:44:49      7           0
    6      -146.085   17:44:49      7           0
    7      -146.084   17:44:49      7           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -311.974   17:44:57      7           0
    2      -201.639   17:44:57      7           0
    3      -150.595   17:44:57      7           0
    4      -143.846   17:44:57      7           0
    5      -143.629   17:44:57      7           0
    6      -143.617   17:44:57      7           0
    7      -143.616   17:44:58      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -308.196   17:45:5      7           0
    2      -230.815   17:45:5      7           0
    3      -166.398   17:45:5      7           0
    4      -150.353   17:45:5      7           0
    5      -149.679   17:45:6      8           0
    6      -149.624   17:45:6      8           0
    7      -149.619   17:45:6      8           0
    8      -149.618   17:45:6      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -325.445   17:45:14      7           0
    2      -227.107   17:45:14      7           0
    3      -160.199   17:45:14      7           0
    4      -148.014   17:45:14      7           0
    5      -147.914   17:45:14      7           0
    6      -147.912   17:45:14      7           0
    7      -147.911   17:45:15      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -341.46   17:45:22      7           0
    2      -240.763   17:45:22      7           0
    3      -171.419   17:45:22      7           0
    4      -156.018   17:45:23      8           0
    5      -155.64   17:45:23      8           0
    6      -155.616   17:45:23      8           0
    7      -155.614   17:45:23      8           0
    8      -155.614   17:45:23      8           0
iteration    LogLik     wall    cpu(sec)   restrained
    1      -324.198   17:45:31      7           0
    2      -222.233   17:45:31      7           0
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# Combinar todos os resultados da validação cruzada em uma única estrutura
results_cv_RR_BLUP <- do.call(rbind, results_list)

# Extrair os GEBVs (Valores Genômicos Empíricos Melhorados) em uma estrutura separada
GEBVS_RR_BLUP <- do.call(rbind, results_cv_RR_BLUP$result)

Results

The object “GEBVS_RR_BLUP” contains the GEBVs for each trait and clone. The table above shows the first five clones and their GEBVs for each trait.

GEBVS_RR_BLUP |>
  group_by(Trait, ID_Clone) |>
  summarise(GEBV = mean(GEBV)) %>%
  pivot_wider(names_from = Trait, values_from = GEBV) %>%
  head() %>%
  kbl(escape = F, align = 'c') |>
  kable_classic("hover", full_width = F, position = "center", fixed_thead = T)
`summarise()` has grouped output by 'Trait'. You can override using the
`.groups` argument.
ID_Clone DMC FRY HI N_Roots Nstem.Plant Plant.Height Root.Di Root.Le ShY StC StY Stem.D
BGM_2042 0.7038150 1.0164613 1.2008957 0.6041832 0.1322925 0.0278615 0.6277447 1.3015786 1.8062028 0.5618611 0.2298328 0.0866096
BGM0368.250437186 1.0245002 -0.2837211 0.3577004 0.2804180 0.0108235 0.0046657 -0.3975744 0.1256635 -1.7309604 0.5791711 -0.0643122 -0.0273916
BGM0424.250437187 0.2115211 -0.0377704 0.1334632 -0.0350450 -0.0203223 0.0091547 -0.3918618 -0.0585051 -0.7509616 0.2799995 -0.0195040 0.0232335
BGM0611.250437190 -0.9318154 -0.1707643 -0.3918168 0.0298179 0.1160142 -0.0264102 -0.2093254 0.4747266 0.0168450 -0.9385506 -0.0590765 -0.0543588
BGM0652.250437861 -0.1509234 0.0003093 -0.0546992 0.0887959 0.0646285 -0.0223745 -0.3808762 0.3680189 0.4192441 0.0304429 -0.0103415 0.0021456
BGM0699.250437199 -0.1214714 -0.5425852 -0.6559413 -0.1781270 -0.0246898 -0.0054335 -0.4278567 0.3523725 -0.2593301 -0.2257905 -0.0832968 0.0384648

Acuracy and MSPE for each trait and repetition:

results_cv_RR_BLUP[-6] |>
  group_by(Trait) %>% 
  summarise_all(mean) %>% 
  arrange(desc(Ac), MSPE) %>% 
  kbl(escape = F, align = 'c') |>
  kable_classic("hover", full_width = F, position = "center", fixed_thead = T)
Trait rep Log Ac MSPE
Root.Le 3 1 0.3616 1.9996
Stem.D 3 1 0.3402 0.0080
ShY 3 1 0.3240 12.6150
StY 3 1 0.3170 0.0702
FRY 3 1 0.3116 1.1666
Plant.Height 3 1 0.3030 0.0078
Root.Di 3 1 0.2948 3.3806
Nstem.Plant 3 1 0.2684 0.0288
HI 3 1 0.2478 11.8660
N_Roots 3 1 0.2462 0.8826
DMC 3 1 0.2446 5.7684
StC 3 1 0.2012 5.9146

The object “result_cv” is divided by repetition. In the “result_cv” objects for each repetition, “Rep” is the number of the repetition, “Log” is a diagnostic indicating if the order of the predicted breeding values matches the order of the adjusted means, “Ac” is the prediction accuracy (correlation between the GEBV and adjusted means), and “MSPE” is the mean square prediction error (the lower, the better).

Let’s now move on to processing each model. Since this can be time-consuming, I’ve separated it into parallel processing and each model into each script:


sessionInfo()
R version 4.3.2 (2023-10-31)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: Ubuntu 22.04.3 LTS

Matrix products: default
BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.10.0 
LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.10.0

locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
 [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
 [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
 [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
 [9] LC_ADDRESS=C               LC_TELEPHONE=C            
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       

time zone: Etc/UTC
tzcode source: system (glibc)

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] kableExtra_1.4.0    cvTools_0.3.3       robustbase_0.99-4-1
 [4] lattice_0.21-9      lubridate_1.9.4     forcats_1.0.0      
 [7] stringr_1.5.1       dplyr_1.1.4         purrr_1.0.2        
[10] readr_2.1.5         tidyr_1.3.1         tibble_3.2.1       
[13] ggplot2_3.5.1       tidyverse_2.0.0     furrr_0.3.1        
[16] future_1.34.0      

loaded via a namespace (and not attached):
 [1] gtable_0.3.6      xfun_0.50         bslib_0.8.0       tzdb_0.4.0       
 [5] vctrs_0.6.5       tools_4.3.2       generics_0.1.3    parallel_4.3.2   
 [9] DEoptimR_1.1-3-1  pkgconfig_2.0.3   lifecycle_1.0.4   compiler_4.3.2   
[13] git2r_0.35.0      munsell_0.5.1     codetools_0.2-19  httpuv_1.6.15    
[17] htmltools_0.5.8.1 sass_0.4.9        yaml_2.3.10       later_1.4.1      
[21] pillar_1.10.1     jquerylib_0.1.4   cachem_1.1.0      parallelly_1.41.0
[25] tidyselect_1.2.1  digest_0.6.37     stringi_1.8.4     listenv_0.9.1    
[29] rprojroot_2.0.4   fastmap_1.2.0     grid_4.3.2        colorspace_2.1-1 
[33] cli_3.6.3         magrittr_2.0.3    withr_3.0.2       scales_1.3.0     
[37] promises_1.3.2    timechange_0.3.0  rmarkdown_2.29    globals_0.16.3   
[41] workflowr_1.7.1   hms_1.1.3         evaluate_1.0.3    knitr_1.49       
[45] viridisLite_0.4.2 rlang_1.1.4       Rcpp_1.0.14       glue_1.8.0       
[49] xml2_1.3.6        svglite_2.1.3     rstudioapi_0.17.1 jsonlite_1.8.9   
[53] R6_2.5.1          systemfonts_1.1.0 fs_1.6.5         

  1. Weverton Gomes da Costa, Pós-Doutorando, Embrapa Mandioca e Fruticultura, ↩︎